مطالعه مقايسه اي ارتباط بين تست CAT و Hs-CRP با ايندكس هاي SPO2 , FEV!, BODE index, و ريت تشديد دوره بيماري COPD

قبادی مراللو, حسن ، بیوک آقازاده, کاترین ، فولادی, نسرین (1390) مطالعه مقايسه اي ارتباط بين تست CAT و Hs-CRP با ايندكس هاي SPO2 , FEV!, BODE index, و ريت تشديد دوره بيماري COPD. در: ERS 21st Annual Congress. 24-28 September 2011, Amsterdam, The Netherlands. , 24-28 September 2011, Amsterdam-Netherlands.

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آدرس اینترنتی رسمی : http://www.ers-education.org/ersMade/abstract_prin...

عنوان انگليسي

A comparative study of the correlations of the COPD assessment test (CAT) scores and high sensitive CRP levels to SPO2, FEV1, BODE index, and exacerbation rate.

خلاصه انگلیسی

Background: High sensitive CRP is used as a marker of systematic inflammation in COPD. Results have shown an inverse relation between serum hs-CRP and FEV1, except for small study which did not report any correlation between hs-CRP level and FEV1. However, we hypothesize that the raised hs-CRP is not closely related to the multiple consequences of COPD. CAT is a simple questionnaire for assessing and monitoring COPD. Thus, this study was undertaken to investigate the correlations between CAT score and SPO2, FEV1, BODE index, and exacerbation rate, and compare it with the correlations to the serum hs-CRP. Method: We studied 60 patients with stable COPD and 15 normal subjects as a control group. SPO2, BODE index, pulmonary function test and exacerbation rate were determined in COPD patients. Serum level of hs-CRP was measured in all patients and the control group. Then, the CAT questionnaire was completed by patients. Results: Hs-CRP level was significantly raised in patients (p=0.005). In these patients, correlations of hs-CRP level with BODE index appeared significant (p=0.008). However, the correlation between hs-CRP with SPO2 and FEV1 did not appear significant (p=0.47, p=0.17respectively). Also, the CAT score correlations with SPO2, FEV1, BODE index, and exacerbation rate in the previous year were all found to be significant (p=0.000, p=0.000, p=0.000, p=0.017, respectively). Conclusion: We conclude that SPO2, FEV1, BODE index and exacerbation rate are more correlated with the CAT scores than with the serum level of hs-CRP in stable COPD patients. The findings of this study should be considered in management of stable COPD.

نوع سند :موضوع کنفرانس یا کارگاه (پوستر )
زبان سند : انگلیسی
نویسنده مسئول :حسن قبادی مراللو
کلید واژه ها:تست ارزيابي برونشيت .ايندكس ساچوراسيون . سطح CRP سرم .ايندكس BODE .
کلید واژه ها (انگلیسی):CAT, COPD, Hs-CRP, BODE index, SPO2, Exacerbation
موضوعات :WF سیستم تنفسی
بخش های دانشگاهی :دانشكده پزشكي > گروه اطفال ، پزشکی اجتماعی
دانشكده پزشكي > گروه داخلی ، قلب ، عفونی
کد شناسایی :2697
ارائه شده توسط : دکتر حسن قبادی
ارائه شده در تاریخ :23 مهر 1390 07:42
آخرین تغییر :05 فروردین 1393 10:17

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