فرشباف خلیلی, عزیزه ، محمدی قلعه بین, بهنام ، شهنازی, مهناز ، اصغری, سلطان ، جوادزاده, یوسف ، آذغانی, پیمان (1395) مقایسه تاثیر کرم واژینال سیر، آویشن شیرازی و کلوتریمازول2% در بهبود واژینیت قارچی: یک کارآزمایی بالینی تصادفی کنترل شده. Iranian Red Crescent Medical Journal ــ 18 (12). ص.ص.1-10. شاپا 2074-1812
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آدرس اینترنتی رسمی : http://ircmj.com/en/articles/16723.html
عنوان انگليسی
Comparing the Effect of Garlic, Zataria multiflora and Clotrimazole Vaginal Cream 2% on Improvement of Fungal Vaginitis: A Randomized Controlled Trial
خلاصه انگلیسی
Abstract Background: Garlic and Zataria multiflora boiss (ZMB) are herbal medicines used traditionally in the treatment of infections, including candidal vaginitis. Objectives: This study aimed to examine the effect of garlic and ZMB vaginal cream 2%, in the treatment and recurrence of candidal vaginitis. Methods: This randomized, double-blinded clinical trial was conducted on240 married womenwith candidal vaginitis. The patients used 5 gr garlic, ZMBor clotrimazole vaginal cream 2% daily, for 7 days. Complaints of the patients, clinical observations and laboratory parameters were recorded before treatment, on days 7 and 30, after treatment. The data were analyzed by SPSS v. 21 through chi-square, Fisher, ANOVA with repeated measures, McNemar and Kruskal-Wallis tests. A P <0.05 was considered significant. Results: Before treatment, all patients had positive candidiasis fungi culture, in both groups (100%). The positive culture was 14.1%, 15.2%, 10.3%, respectively, on day 7 after treatment and 2.6%, 0%, 0% on day 30, after treatment with garlic, ZMB and clotrimazole, respectively (P < 0.001). No significant differences were observed between groups on days 7 (P = 0.69) and 30 (P = 0.21) after treatment, in culture results. There were no significant differences between groups, in terms of patient complaints and clinical observations before intervention, at days 7 and 30 after treatment (P > 0.05). Mean scores of candidal symptoms reduced significantly in all groups at on 7 and 30, after treatment (P < 0.001). Conclusions: Garlic and ZMB vaginal cream 2% can be used as an effective treatment option in cases of drug resistance and, also, by the people who are interested in treating with herbal medicines.
نوع سند : | مقاله |
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زبان سند : | انگلیسی |
نویسنده اول : | عزیزه فرشباف خلیلی |
نویسنده : | بهنام محمدی قلعه بین |
نویسنده : | مهناز شهنازی |
نویسنده مسئول : | سلطان اصغری |
نویسنده : | یوسف جوادزاده |
نویسنده : | پیمان آذغانی |
ضریب تاثیر و نمایه مجلات: | Impact Factor (2016) 0.865 Indexed in: ISI, Pubmed, Embase, Open-J-Gate, DOAJ, Index Copernicus,Google Scholar, ISC, MagIran, SID |
کلیدواژه ها (انگلیسی): | Vaginitis , Candidiasis , Garlic, Clotrimazole , Herbal Medicine |
موضوعات : | QV فارماکولوژی QW میکروب شناسی و ایمنی شناسی WP بیماریهای زنان |
بخش های دانشگاهی : | دانشكده پزشكي > گروه علوم پایه > بخش انگل شناسی |
کد شناسایی : | 7990 |
ارائه شده توسط : | دکتر بهنام محمدی قلعه بین |
ارائه شده در تاریخ : | 04 آذر 1395 08:14 |
آخرین تغییر : | 02 دی 1397 16:48 |
فقط پرسنل کتابخانه صفحه کنترل اسناد