title

اثر شل کنندگی تیموس ولگاریس بر روی زنجیره تراشه خوکچه هندی و مکانیسم احتمالی آن

بسکابادی, محمد حسین ، اصلانی, محمدرضا ، کیانی, سحر (1384) اثر شل کنندگی تیموس ولگاریس بر روی زنجیره تراشه خوکچه هندی و مکانیسم احتمالی آن. Phytotherapy Research ــ 20 (1). ص.ص.28-33. شاپا 1099-1573

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آدرس اینترنتی رسمی : http://onlinelibrary.wiley.com/doi/10.1002/ptr.179...


عنوان انگليسي

Relaxant Effect of Thymus vulgaris on Guinea-pig Tracheal Chains and its Possible Mechanism(s)

خلاصه انگلیسی

Thymus vulgaris for the treatment of respiratory diseases is indicated widely, and relaxant effects on smooth muscle have been shown previously. In the present study, the relaxant effects of macerated and aqueous extracts of Thymus vulgaris on tracheal chains of guinea-pigs were examined using cumulative concentrations of macerated and aqueous extracts in comparison with saline (as the negative control) and theophylline (as the positive control). The relaxant effects of four cumulative concentrations of macerated and aqueous extracts (0.25, 0.5, 0.75 and 1.0 g %) in comparison with saline (as the negative control) and four cumulative concentrations of theophylline (0.25, 0.5, 0.75 and 1.0 mM; as the positive control) were examined for their relaxant effects on precontracted tracheal chains of guinea-pig by 60 mM KCl and 10 μM methacholine in two different conditions: non-incubated tissues and incubated tissues with 1 μM propranolol and 1 μM chlorphenamine. There were significant correlations between the relaxant effects and the concentrations for both extracts and theophylline in all experimental groups (p < 0.01 to p < 0.001). These results demonstrated a potent relaxant effect of Thymus vulgaris on guinea-pig tracheal chains that was comparable to theophylline at the concentrations used.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده مسئول :محمد حسین بسکابادی
نویسنده :محمدرضا اصلانی
نویسنده :سحر کیانی
اطلاعات اضافی :Impact Factor (2006) 1.144 Indexed in: ISI, Pubmed/Medline/Index Medicus, Scopus, Chemical Abstracts, Abstracts in Anthropology (Sage) , Abstracts on Hygiene & Communicable Diseases (CABI) , AGRICOLA Database (National Agricultural Library) , Agricultural & Environmental Science Database (ProQuest) , BIOBASE: Current Awareness in Biological Sciences, Biological Abstracts (Clarivate Analytics) , Embase
کلید واژه ها (انگلیسی):Thymus vulgaris; bronchodilatory; guinea-pig trachea.
موضوعات :QV فارماکولوژی > QV 767 داروسازی سنتی
QT فیزیولوژی
QV فارماکولوژی
WF سیستم تنفسی
بخش های دانشگاهی :دانشكده پزشكي > گروه علوم پایه > بخش فیزیولوژی
کد شناسایی :8817
ارائه شده توسط : دکتر محمد رضا اصلانی
ارائه شده در تاریخ :28 تیر 1396 07:32
آخرین تغییر :28 تیر 1396 07:43

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