title

مصرف الکل و سرطان معده: متاآنالیز داده های منتشر شده در مقابل تجزیه و تحلیل داده های فردی (پروژه آنالیز تجمیعی سرطان معده)

Ferro, Ana ، Morais, Samantha ، Rota, Matteo ، Pelucchi, Claudio ، Bertuccio, Paola ، Bonzi, Rossella ، Galeone, Carlotta ، Zhang, Zuo-Feng ، Matsuo, Keitaro ، Ito, Hidemi ، Hu, Jinfu ، Johnson, Kenneth C ، Yu, Guo-Pei ، Palli, Domenico ، Ferraroni, Monica ، Muscat, Joshua ، ملک زاده, رضا ، Ye, Weimin ، Song, Huan ، Zaridze, David ، Maximovitch, Dmitry ، Fernández de Larrea, Nerea ، Kogevinas, Manolis ، Vioque, Jesus ، Navarrete-Muñoz, Eva M ، پاک سرشت, محمدرضا ، پورفرضی, فرهاد ، Wolk, Alicja ، Orsini, Nicola ، Bellavia, Andrea ، Håkansson, Niclas ، Mu, Lina ، Pastorino, Roberta ، Kurtz, Robert C ، درخشان, محمدحسین ، Lagiou, Areti ، Lagiou, Pagona ، Boffetta, Paolo ، Boccia, Stefania ، Nagri, Eva ، La Vecchia, Carlo ، Peleteiro, Bárbara ، Lunet, Nuno (1397) مصرف الکل و سرطان معده: متاآنالیز داده های منتشر شده در مقابل تجزیه و تحلیل داده های فردی (پروژه آنالیز تجمیعی سرطان معده). Cancer Epidemiology ــ 54 (2018). ص.ص.125-132. شاپا 1877-7821

[img] متنی - نسخه چاپ شده
محدود به فقط پرسنل سامانه

704kB

آدرس اینترنتی رسمی : https://www.clinicalkey.com/#!/content/playContent...


عنوان انگليسي

Alcohol intake and gastric cancer: Meta-analyses of published data versus individual participant data pooled analyses (StoP Project)

خلاصه انگلیسی

Background Individual participant data pooled analyses allow access to non-published data and statistical reanalyses based on more homogeneous criteria than meta-analyses based on systematic reviews. We quantified the impact of publication-related biases and heterogeneity in data analysis and presentation in summary estimates of the association between alcohol drinking and gastric cancer. Methods We compared estimates obtained from conventional meta-analyses, using only data available in published reports from studies that take part in the Stomach Cancer Pooling (StoP) Project, with individual participant data pooled analyses including the same studies. Results A total of 22 studies from the StoP Project assessed the relation between alcohol intake and gastric cancer, 19 had specific data for levels of consumption and 18 according to cancer location; published reports addressing these associations were available from 18, 5 and 5 studies, respectively. The summary odds ratios [OR, (95%CI)] estimate obtained with published data for drinkers vs. non-drinkers was 10% higher than the one obtained with individual StoP data [18 vs. 22 studies: 1.21 (1.07–1.36) vs. 1.10 (0.99–1.23)] and more heterogeneous (I 2 : 63.6% vs 54.4%). In general, published data yielded less precise summary estimates (standard errors up to 2.6 times higher). Funnel plot analysis suggested publication bias. Conclusion Meta-analyses of the association between alcohol drinking and gastric cancer tended to overestimate the magnitude of the effects, possibly due to publication bias. Additionally, individual participant data pooled analyses yielded more precise estimates for different levels of exposure or cancer subtypes.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده :رضا ملک زاده
نویسنده :محمدرضا پاک سرشت
نویسنده :فرهاد پورفرضی
نویسنده :محمدحسین درخشان
اطلاعات اضافی :IF(2016) 2.343 Indexed in: ISISciSearch/Science Citation Index Expanded , Journal Citation Reports - Science Edition, Pubmed/Medline, Scopus, Current Contents / Clinical Medicine,
کلیدواژه ها (انگلیسی):Alcohol; Gastric cancer; Individual participant data; Meta-analysis; Pooled analysis; Publication bias
موضوعات :QZ آسیب شناسی
WI سیستم گوارشی
بخش های دانشگاهی :دانشكده پزشكي > گروه اطفال ، پزشکی اجتماعی
کد شناسایی :10094
ارائه شده توسط : خانم صغری گلمغانی
ارائه شده در تاریخ :12 خرداد 1397 09:41
آخرین تغییر :12 خرداد 1397 10:37

فقط پرسنل کتابخانه صفحه کنترل اسناد

Document Downloads

More statistics for this item...