title

سیگار کشیدن و سرطان معده: متاآنالیز داده های منتشر شده در مقابل تجزیه و تحلیل جمع آوری شده از داده های فردی (پروژه آنالیز تجمیعی سرطان معده)

Ferro, Ana and Morais, Samantha and Rota, Matteo and Pelucchi, Claudio and Bertuccio, Paola and Bonzi, Rossella and Galeone, Carlotta and Zhang, Zuo-Feng and Matsuo, Keitaro and Ito, Hidemi and Hu, Jinfu and Johnson, Kenneth C and Yu, Guo-Pei and Palli, Domenico and Ferraroni, Monica and Muscat, Joshua and ملک زاده, رضا and Ye, Weimin and Song, Huan and Zaridze, David and Maximovitch, Dmitry and Aragonés, Nuria and Castaño-Vinyals, Gemm and Vioque, Jesus and Navarrete-Muñoz, Eva M and پاک سرشت, محمدرضا and پورفرضی, فرهاد and Wolk, Alicja and Orsini, Nicola and Bellavia, Andrea and Håkansson, Niclas and Mu, Lina and Pastorino, Roberta and Kurtz, Robert C and درخشان, محمدحسین and Lagiou, Areti and Lagiol, Pagona and Boffetta, Paolo and Boccia, Stefania and Negri, Eva and Vecchia, CCarlo La and Peleteiro, Bárbara and Lunet, Nuno (1397) سیگار کشیدن و سرطان معده: متاآنالیز داده های منتشر شده در مقابل تجزیه و تحلیل جمع آوری شده از داده های فردی (پروژه آنالیز تجمیعی سرطان معده). European Journal of Cancer Prevention ــ 27 (3). pp. 197-204. شاپا 0959-8278

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Title

Tobacco smoking and gastric cancer: Meta-Analyses of published data versus pooled analyses of individual participant data (StoP Project)

English Abstract

Tobacco smoking is one of the main risk factors for gastric cancer, but the magnitude of the association estimated by conventional systematic reviews and meta-Analyses might be inaccurate, due to heterogeneous reporting of data and publication bias. We aimed to quantify the combined impact of publication-related biases, and heterogeneity in data analysis or presentation, in the summary estimates obtained from conventional meta-Analyses. We compared results from individual participant data pooled-Analyses, including the studies in the Stomach Cancer Pooling (StoP) Project, with conventional meta-Analyses carried out using only data available in previously published reports from the same studies. Fromthe 23 studies in the StoP Project, 20 had published reports with information on smoking and gastric cancer, but only six had specific data for gastric cardia cancer and seven had data on the daily number of cigarettes smoked. Compared to the results obtained with the StoP database, conventional meta-Analyses overvalued the relation between ever smoking (summary odds ratios ranging from 7 higher for all studies to 22 higher for the risk of gastric cardia cancer) and yielded less precise summary estimates (SE �2.4 times higher). Additionally, funnel plot asymmetry and corresponding hypotheses tests were suggestive of publication bias. Conventional meta-Analyses and individual participant data pooled-Analyses reached similar conclusions on the direction of the association between smoking and gastric cancer. However, published data tended to overestimate the magnitude of the effects, possibly due to publication biases and limited the analyses by different levels of exposure or cancer subtypes. European Journal of Cancer Prevention 27:197-204 Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

Item Type:Article
زبان سند : انگلیسی
نویسنده :رضا ملک زاده
نویسنده :محمدرضا پاک سرشت
نویسنده :فرهاد پورفرضی
نویسنده :محمدحسین درخشان
Additional Information:IF: 2.556 Indexed in: ISI-Science Citation Index Expanded Pubmed/Medline/Index Medicus, Scopus, Current Contents - Clinical Medicine,
کلیدواژه ها (انگلیسی):Article; human; Medline; priority journal; publishing; smoking; stomach cancer; systematic review; Web of Science
Subjects:QZ Pathology
WF Respiratory System
WI Digestive System
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
ID Code:10095
Deposited By: MS Soghra Golmaghani
Deposited On:12 Mar 1397 10:30
Last Modified:12 Mar 1397 10:33

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