title

بررسی شیوع گونه های اکینوکوکوس در سگ سانان دشت مغان با استفاده از تست کوپرآنتی ژن الیزا

زارع بیدکی, مجید and موبدی, ا and نداف, س and کیا, ای and محمودی, م and پیازک, ن and نکویی, ه and صادقیه اهری, سعید and حبیب زاده, شهرام and سیاوشی, محمد رضا (1388) بررسی شیوع گونه های اکینوکوکوس در سگ سانان دشت مغان با استفاده از تست کوپرآنتی ژن الیزا. Iranian Journal of Public Health ــ 38 (1). pp. 112-118. شاپا 0304-4556

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Title

Prevalence of Echinococcus spp. Infection Using Coproantigen ELISA among Canids of Moghan Plain, Iran

English Abstract

Background: Echinococcosis is one of the most important helminthic zoonotic diseases in Iran. Intestinal Scraping Technique (IST), the traditional method for diagnosis of infection in definitive hosts, has many disadvantages including low susceptibility and being expensive, hazardous and laborious. Detection of coproantigens in fecal samples by enzyme-linked immunosorbent assay (CA-ELISA) is known as a useful tool for intravital mass-screening of definitive host populations. This study was performed to determine the prevalence of Echinococcus spp. infection among canids in Moghan plain, the only area in Iran known as endemic for E. multilocularis. Methods: One hundred thirty eight fecal samples were collected from red foxes and domestic dogs in three counties of Moghan plain namely Pars Abad, Bileh Savar and Germi. The samples were examined using an ELISA, designed for the detection of Echinococcus-specific coproantigen and the formalin-ether concentration method as well. Results: Totally, out of 138 fecal samples, 27 (21.6%) turned positive for Echinococcus coproantigen. coproantigen was detected in 16.7% and 27.1% of red foxes and domestic dogs, respectively. Formalin-ether concentration method revealed that 43 (31.2%) of samples harbored at least one parasitic helminth, but Taenia eggs were detected only in 3 fecal samples. Since coproantigen presence reflects current intestinal infection with adult worms, CA-ELISA can be regarded as one of the most useful immunological tools for diagnosis of Echinococcus infection. Besides, the high susceptibility, less expense and rapidity make it the method of choice for epidemiological surveys in endemic areas of Iran.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :مجید زارع بیدکی
نویسنده مسئول :محمد رضا سیاوشی
Additional Information:Impact Factor=0.341 Indexed in :ISI , EMBASE, Chemical Abstracts, SCOPUS, DOAJ , Magiran, SID and IranMedex
کلیدواژه ها (انگلیسی):Coproantigen, Echinococcosis, Echinococcus, CA-ELISA, Canids, Iran
Subjects:QX Parasitology
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
Faculty of Medicine > Department of Internal Medicine , Cardiology , Infectious
ID Code:1047
Deposited By: Dr Shahram Habibzadeh
Deposited On:09 Dec 1388 10:27
Last Modified:20 Feb 1399 16:47

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