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بررسی میزان اثربخشی واکسیناسیون هپاتیت b دربیماران دیالیزی شهرستان اردبیل

محمدی کبار, سوسن ، حسینی نیا, سعید ، محمدی کبار, یوسف ، برومند داشقاپو, محمد (1397) بررسی میزان اثربخشی واکسیناسیون هپاتیت b دربیماران دیالیزی شهرستان اردبیل. Journal of Renal Injury Prevention ــ 8 (1). ص.ص.10-6. شاپا 2345-2781

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عنوان انگليسی

An investigation of the efficacy on hepatitis B vaccination in hemodialysis patients in Ardabil, Iran

خلاصه انگلیسی

Introduction: Hemodialysis patients usually demonstrate lower immune response to hepatitis B vaccine compared to non-uremic population. Objectives: The present study aimed to determine the level of response to hepatitis B vaccination in patients under hemodialysis. Patients and Methods: This study was conducted on 172 live patients receiving hemodialysis in the dialysis department of Buali hospital in Ardabil, Iran (2015). To analyze their response to the vaccine, their vaccination titers were investigated. Before vaccination, the serological markers of hepatitis B and C were checked in all of the patients. Those for whom HBsAg and HBsAb results were negative and had not received the vaccinein the past entered the study. The patients received a double dose of hepatitis B vaccine at 0, 1, and 6 months after the beginning of dialysis. The response to the vaccine was investigated by measuring the level of patients’ hepatitis B antibody one month after receiving the last dose of the vaccine. Results: Seventy patients (40% of the total) displayed a proper immune response to the vaccine, 34 patients (19.8%) were without, and 68 patients (39.5%) were identified to have poor response. The results of Pearson’s correlation test indicated that there is a negative correlation between the patients’ age and their response to the vaccine. Conclusion: The results of this study indicated that higher age is one of the factors that reduce the effectiveness of hepatitis B vaccine in hemodialysis patients.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده مسئول :سوسن محمدی کبار
نویسنده :سعید حسینی نیا
نویسنده :یوسف محمدی کبار
نویسنده :محمد برومند داشقاپو
ضریب تاثیر و نمایه مجلات:Indexed in: ESCI, Scopus
کلیدواژه ها (انگلیسی):Vaccination, Hemodialysis, Hepatitis B, Renal failure
موضوعات :WJ سیستم ادراری
بخش های دانشگاهی :دانشكده پزشكي > گروه داخلی ، قلب ، عفونی
کد شناسایی :11064
ارائه شده توسط : دکتر سعید حسینی نیا
ارائه شده در تاریخ :21 اسفند 1398 17:47
آخرین تغییر :21 اسفند 1398 17:47

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