آیا پروتئین HS-CRP یک پیش بینی کننده شدت بیماری راه هوائی در جانبازان شیمیائی ریوی است؟

محمدزاده لاری, شهرزاد and عطاران, داود and توحیدی, محمد and اثنی عشری, امیر and قبادی مراللو, حسن and خواجه دلوئی, محمد and آیت اللهی, حسین (1388) آیا پروتئین HS-CRP یک پیش بینی کننده شدت بیماری راه هوائی در جانبازان شیمیائی ریوی است؟. در: سخنرانی کلاسی (E. Communication), شهریور 1388, وین - اتریش.

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Official URL: http://ers.E-Communication Session: ERS 2009


Highly sensitive C-reactive protein: is it a predictor of airway disease severity in mustard lung patients?

English Abstract

Introduction: Respiratory problems are the most common late complication of Sulfur Mustard exposure. It was the first study that designed to evaluate the relationship between serum highly sensitive C-reactive protein levels (hs-CRP) as an inflammatory marker and severity of airway disease in chemically injured patients (CIPs) suffering from chronic obstructive pulmonary disease (COPD). Methods and materials: Fifty consecutively CIPs with stable COPD and mean age 46.3±9.18 years were enrolled in this study. Also 30 healthy men were considered as control group and their age and body mass index were matched. The following parameters were evaluated: spirometry, arterial blood gasometry, 6 minute walk distance, BODE index, ST George Respiratory Questionnaire (SGRQ). Serum hs-CRP levels were measured in both patient and control groups. Results: In case group, mean FEV1 was 2.14± 0.76 lit. (58.98± 17.51 %pred). Fifty-four percent of patients were in moderate stage of COPD .The mean serum hs-CRPlevel was 9.4± 6.78 mg/l in case group. There was significant differences in serum hs-CRP levels between case and control groups (p<0.001).There was significant inverse correlation between serum hs-CRPlevel and FEV1 (p=0.01).Also hs-CRP level had significant correlation with Global initiative for chronic Obstructive Lung Disease (GOLD) stages (r=0.45, p<0.001) Conclusion: According to this study, it is proposed that serum hs-CRP level is increased in CIPs with COPD and it have direct correlation with disease severity.

Item Type:Conference or Workshop Item (Lecture)
زبان سند : انگلیسی
نویسنده مسئول :شهرزاد محمدزاده لاری
Additional Information:کد مقاله: E3147
کلیدواژه ها (انگلیسی):hs_CRP , موستارد , راه هوائی.
Subjects:WF Respiratory System
Divisions:Faculty of Medicine > Department of Internal Medicine , Cardiology , Infectious
ID Code:1138
Deposited By: Dr Hassan Ghobadi
Deposited On:20 Dec 1388 09:58
Last Modified:15 Oct 1398 10:52

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  • آیا پروتئین HS-CRP یک پیش بینی کننده شدت بیماری راه هوائی در جانبازان شیمیائی ریوی است؟. (deposited 20 Dec 1388 09:58) [Currently Displayed]

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