بیماری پارکینسون و خطر شکستگی هیپ: مرور سیستماتیک و متاآنالیز

حسین زاده, علی and خلیلی, ملاحت and صدیقی, بهناز and ایرانپور, سهراب and حقدوست, علی اکبر (1397) بیماری پارکینسون و خطر شکستگی هیپ: مرور سیستماتیک و متاآنالیز. Acta Neurologica Belgica ــ 118 (2). pp. 201-210. شاپا 0300-9009

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Official URL: https://link.springer.com/article/10.1007/s13760-0...


Parkinson’s disease and risk of hip fracture: systematic review and meta-analysis

English Abstract

The relationship between Parkinson’s disease (PD) and risk of hip fracture yielded inconsistent results. Therefore, we conducted the present systematic review and meta-analysis of published observational studies to assess the association between PD and risk of hip fracture. PubMed, ISI, EMBASE, and Cochrane databases were searched systematically to identify studies assessing the relationship between PD and the risk of hip fracture up to July 01, 2017. In addition, to find related articles, the reference section of retrieved articles was checked. Random-effects model was used for calculation of pooled hazard ratio (HR) and 95% confidence intervals (CI). Thirteen independent studies containing 564,947 participants were included in the meta-analysis. The overall results of included studies showed PD to be associated with the risk of hip fracture (HRoverall = 3.13, 95% CI 2.53–3.87) in women 3.11 (2.51–3.86) and men 2.60 (2.19–3.09). Our meta-analysis showed the direct association between PD and the risk of hip fracture in both men and women. However, due to the limitations of this study, further well-designed studies are required to confirm our findings.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :علی حسین زاده
نویسنده :بهناز صدیقی
نویسنده :سهراب ایرانپور
نویسنده مسئول :علی اکبر حقدوست
Additional Information:Impact Factor (2017) 2.072 Indexed in: ISI, Pubmed/Medline/Index Medicus, Scopus, Embase, Google Scholar, Current Contents/Clinical Medicine,
کلیدواژه ها (انگلیسی):Parkinson’s disease , Hip fracture , Meta-analysis , Risk factor
Subjects:WE Musculoskeletal system
WL Nervous system
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
ID Code:11455
Deposited By: Dr Sohrab Iranpour
Deposited On:16 Nov 1397 12:20
Last Modified:16 Nov 1397 12:20

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