مطالعه مقایسه ای کتوفول و تیوپنتال سدیم در بیماران تحت دیلاتاسیون با بیهوشی عمومی

عنوان انگليسی

Comparative Study of Ketofol and Thiopental Sodium in Patients undergoing Dilation and Curettage by General Anesthesia

خلاصه انگلیسی

considering that the combined drug, Keto fol has been used and its effcacy observed in patients, we have aimed to compare the effects of ketofol and thiopental sodium on patients who are undergoing dilatation and curettage. This study was conducted as a randomized controlled clinical trial. In this study, 150 patients undergoing dilatation and curettage after classifcation were randomly selected and enrolled. The frst group received ketofol, while thiopental sodium was administered to the second group. Any change in he- modynamics or respiratory distress, including the occur- rence of apnea or hypotension, desaturation and the need for respiratory support were recorded in both groups. Fi- nally, after the completion of the surgery and transfer to the recovery room, the recovery rate of each group was recorded, and once they were conscious and alert, were questioned about their satisfaction. All of the patient in- formation was entered into the SPSS v18 software, and the data were analyzed. This study was conducted on 150 patients undergoing curettage; the mean ages in the frst and second groups were 31.82 ± 9.18 and 33.64 ± 11.39 years, respectively. Ninety two percent of patients in the ketofol group and 100% of the patients in the thiopental sodium group experienced apnea and needed respiratory support. About 25.3% of patients in the ketofol group and 44% of patients in the thiopental group required a re-dose of the drug for the anesthetic process. The dura- tion of recovery in the ketofol group was lower than the other group. About 2.7% of the patients in the ketofol group and 12% of the patients in the thiopental group had hallucinations and delusions at the end of the opera- tion Six patients in the thiopental group also had hiccups. The results of the present study showed that ketofol is a better drug than thiopental because of the duration of an- esthesia, reducing the need for medication, the incidence of apnea, and the complications of anesthesia

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