بررسی ANA در کودکان با لیشمانیوز احشایی

عنوان انگليسی

Anti Nuclear Anti Body (Ana) in Visceral Leishmaniasis

خلاصه انگلیسی

Background: The ANA test is a blood test that is commonly used for evaluating of autoimmune or connective tissue disorders. Visceral leishmaniasis is a chronic infectious diseases wich the cellular Immune mechanisms responsible for the control of leishmania infections.This study attempted to investigate the ANA in leishmaniasis, since there was a probability of observing highly positive ANA in this disease. methods: In this study, we collected samples of blood of children who were infected by visceral leishmaniasis .The number of samples was 26 and was collected from three hygienic centers in Ardebil, Meshkin and Germi within 1.5 years. In one sample the DAT of serum was negative, but in the biopsy of bone marrow the leishman's body was reported. The participants were 9 (34.6%) females and 17 (65.4%) males and their ages varied from 5 months to 5 years (mean 21 months). Results: in the 11 cases (42.3%) the ANA test was positive and in 15 cases (57.7%) was negative. The most frequent of positive ANA titers in 2 cases (7.7%) was 14 and the highest titer was 50. ANA in 5 cases of females (55.6%) and in 6 cases of males (35.6%) was positive. Conclusion study indicates that visceral leishmaniasis is an infectious disease which in the antinuclear antibody (ANA) test can be positive. Presence of positive ANA test in visceral leishmaniasis probably be due to disease pathogenesis and changes in immune system and it's disorders.

Document Downloads