title

بررسی مروری و متاآنالیز روی اپیدمیولوژی مقاومت آنتی بیوتیک ویبريو کلرا در ایران

یوسفی اوروند, ارشید and واعظ, حمید and صاحبکار, امیر حسین and خادمی, فرزاد (1398) بررسی مروری و متاآنالیز روی اپیدمیولوژی مقاومت آنتی بیوتیک ویبريو کلرا در ایران. Annali di Igiene, Medicina Preventiva e di Comunità ــ 31 (3). pp. 279-290. شاپا 1120-9135

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Title

A systematic review and meta-analysis on the epidemiology of antibiotic resistance of Vibrio cholerae in Iran

English Abstract

Background. Cholera, an acute diarrheal disease caused by Vibrio cholerae (V. cholerae), is an endemic disease and a major public health problem in Iran. Antibiotic therapy can decrease duration of the disease, transmission of infection and contamination of the environment. Considering different pattern of V. cholerae antibiotic resistance around the world, the aim of the current systematic review and meta-analysis was to evaluate the prevalence of antibiotic resistance of V. cholerae in Iran. Methods. A systematic review of the literature was performed using related keywords in the electronic national and international databases including SID, Irandoc, Iran Medex and Magiran as well as PubMed, Scopus, Google Scholar and ISI web of knowledge. Up to July 31, 2018, 27 eligible papers were included in our meta-analysis based on the defined inclusion criteria. Results. V. cholerae O1 was the most prevalent strain isolated in Iran and exhibited a high resistance rate against numerous antibiotics including chloramphenicol (33.6%), oxytetracycline (40.2%), trimethoprim/ sulphamethoxazole (86%), tetracycline (34.5%), furazolidone (69.8%), streptomycin (93.8%), polymyxin (80.7%), ampicillin (32.1%), nalidixic acid (88.9%), kanamycin (29%) and amoxicillin (30.5%). Conclusion. According to the meta-analysis results, antibiotic therapy with ciprofloxacin, doxycycline, erythromycin, gentamicin, azithromycin, cefixime and cefepime could be effective for the treatment of severe cases of cholera in Iran.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :ارشید یوسفی اوروند
نویسنده :حمید واعظ
نویسنده :امیر حسین صاحبکار
نویسنده مسئول :فرزاد خادمی
Additional Information:Idexing in: PubMed/MedLine, Index Medicus, Scopus
کلیدواژه ها (انگلیسی):Antibiotic resistance; Iran; V. cholerae
Subjects:QW Microbiology and Immunology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:11824
Deposited By: دکتر فرزاد خادمی
Deposited On:05 Mar 1398 11:40
Last Modified:05 Mar 1398 11:40

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