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مقایسه اثر زینک سولفات و شبه دارو در درمان تاکی پنه و تب در کودکان 2 تا 23 ماه با برونشیت حاد

احدی, عادل ، میرزا رحیمی, مهرداد ، براک, منوچهر ، صادقیه اهری, سعید ، ریحانیان ماسوله, مریم (1399) مقایسه اثر زینک سولفات و شبه دارو در درمان تاکی پنه و تب در کودکان 2 تا 23 ماه با برونشیت حاد. international journal of clinical trials ــ 7 (2). ص.ص.50-54. شاپا 2349-3259

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عنوان انگليسی

Comparing the effect of zinc gluconate and placebo in the treatment of tachypnea, dyspnea and fever in children aged 2 to 23 months with acute bronchiolitis

خلاصه انگلیسی

Background: Acute viral bronchiolitis is the most common infection of the lower respiratory tract in infants under 2 years and is one of the reasons for their admission all around the world. The aim of this study was comparing the effect of zinc gluconate and placebo in the treatment of tachypnea, dyspnea and fever in children aged 2 to 23 months with acute bronchiolitis. Methods: This randomized clinical trial study has been done on 100 infants aged 2 to 32 months with the diagnosis of bronchiolitis who divided in two groups. 50 patients received zinc gluconate and 50 patients received placebo. The symptoms and sign of the disease at baseline and then at 24, 72, and 7 days after starting treatment and duration of hospitalization were compared between the two groups. Results: The treatment and placebo groups were similar in respect to mean age and gender distribution. Two groups were similar in terms of clinical symptoms and signs at the time of admission. Bronchiolitis recovery was better in the treatment group than in the placebo group. This positive effect was statistically significant for vising (p=0.023) and rhinorrhea (p=0.027) at 72 hours after starting treatment. The mean duration of hospitalization was significantly less in the treatment group than in the placebo group (4.14±1.21 versus 4.64±1.2 days; p=0.016). Conclusions: Results showed that the use of zinc gluconate as a zinc supplement in infants with acute bronchiolitis could improve their clinical symptoms and signs and decrease the duration of hospitalization.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :عادل احدی
نویسنده مسئول :مهرداد میرزا رحیمی
نویسنده :منوچهر براک
نویسنده :سعید صادقیه اهری
نویسنده :مریم ریحانیان ماسوله
کلیدواژه ها (انگلیسی):Acute bronchiolitis, Zinc gluconate, Infants
موضوعات :WS بیماریهای کودکان
بخش های دانشگاهی :دانشكده پزشكي > گروه اطفال ، پزشکی اجتماعی
کد شناسایی :12881
ارائه شده توسط : دکتر مهرداد میرزارحیمی
ارائه شده در تاریخ :08 اردبهشت 1399 10:13
آخرین تغییر :08 اردبهشت 1399 10:13

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