نامه به سردبیر جدا کردن رکتوم و پوشش پروستات و نتایج محیطی پس از تزریق ژل در طول کاشت براکی تراپی با دز ریت پایینً

عنوان انگليسی

: Letter to the editor” Rectal spacing, prostate coverage, and periprocedural outcomes after hydrogel spacer injection during low-dose-rate brachytherapy implantation”

خلاصه انگلیسی

With interest, we read the recent paper by Kahn et al., (1) reporting dosimetric impact and periprocedural outcomes after transperineal injection of hydrogel spacer (DuraSeal Dural Sealant System; Covidien, Mansfield, MA) during iodine-125 low-dose-rate (LDR) prostate brachytherapy. They observed that using hydrogel spacer creates a significant distance between the rectum and prostate 13.9 � 5.2 mm vs. 6.5 � 5.0 mm ( p!0.0001), resulting in statistically significant reduction in the dose to 1 cc, 2 cc, and 5 cc of the rectum relative to prescription dose (1). These data are in line with previous reports, investigating dosimetric impact of hydrogel spacers during prostate brachytherapy (2). In addition, after median followup of 2 years, there was no significant difference in rectal toxicity between hydrogel and nonhydrogel group (1). To the best of our knowledge, this is the first study reporting late rectal toxicity after hydrogel spacer injection during iodine-125 LDR prostate brachytherapy; however, there are some methodological issues that need to be taken into account

Document Downloads