title

تأثیر داروهای گیاهی در چاقی و سندرم متابولیک: بررسی سیستماتیک و متا آنالیز آزمایشات بالینی

پیاب, مولود ، حسنی رنجبر, شیرین ، شهبال, نازیلا ، قربانی, مصطفی ، آل طاها, آزاده ، حقی امین جان, حامد ، سلطانی, اکبر ، خاتمی, فاطمه ، نیکفر, شکوفه ، حسنی, شکوفه ، عبدالهی, محمد ، لاریجانی, باقر (1398) تأثیر داروهای گیاهی در چاقی و سندرم متابولیک: بررسی سیستماتیک و متا آنالیز آزمایشات بالینی. Phytotherapy Research ــ 34 (3). ص.ص.526-545. شاپا 1099-1573

متن کامل

[img] متنی - نسخه چاپ شده
محدود به فقط پرسنل سامانه

2MB

آدرس اینترنتی رسمی : https://onlinelibrary.wiley.com/doi/abs/10.1002/pt...


عنوان انگليسی

Effect of the herbal medicines in obesity and metabolic syndrome: A systematic review and meta‐analysis of clinical trials

خلاصه انگلیسی

Obesity is a medical situation in which excess body fat has gathered because of imbalance between energy intake and energy expenditure. In spite of the fact that the variety of studies are available for obesity treatment and management, its "globesity" still remains a big challenge all over the world. The current systematic review and meta-analysis aimed to evaluate the efficacy, safety, and mechanisms of effective herbal medicines in the management and treatment of obesity and metabolic syndrome in human. We systematically searched all relevant clinical trials via Web of Science, Scopus, PubMed, and the Cochrane database to assess the effects of raw or refined products derived from plants or parts of plants on obesity and metabolic syndrome in overweight and obesity adult subjects. All studies conducted by the end of May 2019 were considered in the systematic review. Data were extracted independently by two experts. The quality assessment was assessed using Consolidated Standards of Reporting Trials checklist. The main outcomes were anthropometric indices and metabolic syndrome components. Pooled effect of herbal medicines on obesity and metabolic syndrome were presented as standardized mean difference (SMD) and 95% confidence interval (CI). A total of 279 relevant clinical trials were included. Herbals containing green tea, Phaseolus vulgaris, Garcinia cambogia, Nigella sativa, puerh tea, Irvingia gabonensis, and Caralluma fimbriata and their active ingredients were found to be effective in the management of obesity and metabolic syndrome. In addition, C. fimbriata, flaxseed, spinach, and fenugreek were able to reduce appetite. Meta-analysis showed that intake of green tea resulted in a significant improvement in weight ([SMD]: -0.75 [-1.18, -0.319]), body mass index ([SMD]: -1.2 [-1.82, -0.57]), waist circumference ([SMD]: -1.71 [-2.66, -0.77]), hip circumference ([SMD]: -0.42 [-1.02, -0.19]), and total cholesterol, ([SMD]: -0.43 [-0.77, -0.09]). In addition, the intake of P. vulgaris and N. sativa resulted in a significant improvement in weight ([SMD]: -0.88, 95 % CI: [-1.13, -0.63]) and triglyceride ([SMD]: -1.67, 95 % CI: [-2.54, -0.79]), respectively. High quality trials are still needed to firmly establish the clinical efficacy of the plants in obesity and metabolic syndrome.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :مولود پیاب
نویسنده مسئول :شیرین حسنی رنجبر
نویسنده :نازیلا شهبال
نویسنده :مصطفی قربانی
نویسنده :آزاده آل طاها
نویسنده :حامد حقی امین جان
نویسنده :اکبر سلطانی
نویسنده :فاطمه خاتمی
نویسنده :شکوفه نیکفر
نویسنده :شکوفه حسنی
نویسنده مسئول :محمد عبدالهی
نویسنده :باقر لاریجانی
ضریب تاثیر و نمایه مجلات:IF: 3.766 Indexed in: ISI, Scopus, PubMed/Medline, Embase
کلیدواژه ها (انگلیسی):herbal medicines; meta-analysis; metabolic syndrome; obesity; randomized controlled trial; systematic review
موضوعات :WD بیماریهای تغذیه و متابولیکی
بخش های دانشگاهی :معاونت تحقیقات و فناوری > مرکز تحقیقاتی علوم دارویی
کد شناسایی :13196
ارائه شده توسط : دکتر حامد حقی امین جان
ارائه شده در تاریخ :30 تیر 1399 09:18
آخرین تغییر :30 تیر 1399 09:18

فقط پرسنل کتابخانه صفحه کنترل اسناد

Document Downloads

More statistics for this item...