دقت سونوگرافی با رزولوشن بالا برای تشخیص هایپرپاراتیروئیدیسم ثانویه در بیماران دیالیزی

Title

The Accuracy of High Resolution Ultrasound Imaging for Detection of Secondary Hyperparathyroidism in Hemodialysis Patients

English Abstract

Background/Objective: Ultrasound is one of the preferred modalities for evaluation of parathyroid glands. This study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. Patients and Methods: From March 2008 to March 2009, ninety-one hemodialysis patients were examined by high resolution ultrasound (14 MHz) of the parathyroid glands in comparison to parathyroid hormone level. Results: In 40/91 (43.9%) patients' sonography showed enlarged parathyroid glands with an average of 8.7 mm. The mean parathyroid hormone level of patients with enlarged parathyroid glands on sonography was 503±450.031 pg/ml. we revealed a significant difference between parathyroid hormone level and enlarged parathyroid glands (p=0.0001). Sensitivity and specificity of sonography for detection secondary hyperparathyroidism were 62.5%, 85.7%, respectively. Conclusion: In conclusion, our study showed that high resolution sonography is a useful noninvasive method for the evaluation of secondary hyperparathyroidism in patients on hemodialysis and that sonographically enlarged glands may be a measure of severity of secondary hyperparathyroidism.

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