title

ناخالصی های ژنوتوکسیک در فراورده های دارویی

جویبان, ابوالقاسم and پارسا خانکندی, حامد (1390) ناخالصی های ژنوتوکسیک در فراورده های دارویی. در: Toxicity and Drug Testing. Genotoxic Impurities in Pharmaceuticals . IntechOpen, UNITED KINGDOM, pp. 387-414. شابک 978-953-51-4363-5

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Title

Genotoxic Impurities in Pharmaceuticals

English Abstract

Modern drug design and testing involves experimental in vivo and in vitro measurement of the drug candidate's ADMET (adsorption, distribution, metabolism, elimination and toxicity) properties in the early stages of drug discovery. Only a small percentage of the proposed drug candidates receive government approval and reach the market place. Unfavorable pharmacokinetic properties, poor bioavailability and efficacy, low solubility, adverse side effects and toxicity concerns account for many of the drug failures encountered in the pharmaceutical industry. Authors from several countries have contributed chapters detailing regulatory policies, pharmaceutical concerns and clinical practices in their respective countries with the expectation that the open exchange of scientific results and ideas presented in this book will lead to improved pharmaceutical products.

Item Type:Book Section
زبان سند : انگلیسی
نویسنده :ابوالقاسم جویبان
نویسنده :حامد پارسا خانکندی
کلیدواژه ها (انگلیسی):, Drug , Pharmaceuticals , Toxicokinetics , Toxicity
Subjects:QV pharmacology > QV 744 Medicinal Chemistry
QV pharmacology > QV 704 Pharmaceutics
Divisions:School of Pharmacy > Department of Medicinal Chemistry
ID Code:14050
Deposited By: Dr Hamed Parsa Khankandi
Deposited On:12 Dec 1399 10:39
Last Modified:12 Dec 1399 10:39

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