شیوع ﺳﻮﯾﻪﻫﺎی ﺳﻮدوﻣﻮﻧﺎس آﺋﺮوژﯾﻨﻮزای ﻣﻘﺎوم ﺑﻪ ﭼﻨﺪ دارو در اردبیل

خلاصه فارسی

زﻣﯿﻨﻪ و ﻫﺪف:ﻣﻘﺎوﻣﺖ آﻧﺘﯽ ﺑﯿﻮﺗﯿﮑﯽ ﺑﺎﮐﺘﺮﯾﺎﯾﯽ در ﺣﺎل ﺗﺒﺪﯾﻞ ﺷﺪن ﺑﻪ ﯾﮏ ﺑﺤﺮان ﺑﻬﺪاﺷﺖ ﻋﻤﻮﻣﯽ در ﺟﻬﺎن اﺳﺖ. ﻫﺪف از اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﺗﻮﺻﯿﻔﯽ-ﻣﻘﻄﻌﯽ، ﺑﺮرﺳﯽﺷﯿﻮع ﺳﻮﯾﻪ ﻫﺎي ﺳﻮدوﻣﻮﻧﺎس آﺋﺮوژﯾﻨﻮزا ﻣﻘﺎوم ﺑﻪ ﭼﻨﺪ دارو در اردﺑﯿﻞ ﺑﻮد. ﺳﻮﯾﻪ 50، ﺗﻌﺪاد 1398ﻣﺎه، ﺑﯿﻦ ﺗﯿﺮ ﺗﺎ اﺳﻔﻨﺪ ﺳﺎل 9 روش ﮐﺎر:در ﻃﻮل ﺳﻮدوﻣﻮﻧﺎس آﺋﺮوژﯾﻨـﻮزا از ﻧﻤﻮﻧـﻪ ﻫـﺎي ﻣﺨﺘﻠـﻒ PDRو XDR ،MDR ﺑﺎﻟﯿﻨﯽ در ﭼﻬﺎر ﺑﯿﻤﺎرﺳﺘﺎن اردﺑﯿﻞ ﺟﻤﻊآوري و ﺷﯿﻮع ﺳﻮﯾﻪ ﻫﺎي ﺳﻮدوﻣﻮﻧﺎس آﺋﺮوژﯾﻨﻮزا ﺑﺮرﺳﯽ ﺷﺪ. ارزﯾﺎﺑﯽ ﻣﻘﺎوﻣﺖ آﻧﺘﯽ ﺑﯿﻮﺗﯿﮑﯽ ﺑﺎﮐﺘﺮي ﺑﺎ اﺳﺘﻔﺎده از روش دﯾﺴﮏ دﯾﻔﯿﻮژن ﺑﻮد. PDRوXDR ،MDR ﯾﺎﻓﺘﻪ ﻫﺎ:در ﻣﻄﺎﻟﻌﻪ ﺣﺎﺿﺮ، ﺷﯿﻮع ﺳﻮﯾﻪ ﻫﺎي ﺳﻮدوﻣﻮﻧﺎس آﺋﺮوژﯾﻨﻮزا درﺻﺪ 14و 40 ،52ﺑﻪ ﺗﺮﺗﯿﺐ ﺑﻮد. ﻧﺘﯿﺠﻪ ﮔﯿﺮي: ﺑﺎ ﺗﻮﺟﻪ ﺑﻪ ﺷﯿﻮع ﺑﺎﻻي ﺳﻮﯾﻪ ﻫﺎي ﻣﻘﺎوم ﺑﻪ ﭼﻨﺪ دارو ﺳﻮدوﻣﻮﻧﺎس آﺋﺮوژﯾﻨﻮزا در اردﺑﯿﻞ، ﻧﻈـﺎرت ﻣـﺪاوم ﺑـﺮ روﻧﺪ ﻣﻘﺎوﻣﺖ آﻧﺘﯽ ﺑﯿﻮﺗﯿﮑﯽ اﯾﺰوﻟﻪ ﻫﺎي ﺑﺎﻟﯿﻨﯽ اﯾﻦ ﺑﺎﮐﺘﺮي ﺑﻪ ﻣﻨﻈﻮر اﻧﺘﺨﺎب ﺑﻬﺘﺮﯾﻦ ﮔﺰﯾﻨﻪ داروﯾﯽ ﺑﺮاي ﺟﻠﻮﮔﯿﺮي از ﺷﮑﺴﺖ درﻣﺎن ﺿﺮوري اﺳﺖ.

عنوان انگليسی

Prevalence of Multidrug-resistantPseudomonas aeruginosa Strains in Ardabil

خلاصه انگلیسی

Background & objectives: Bacterial antibiotic resistance is becoming a global health crisis. The aim of this descriptive, cross-sectional study was to investigate the prevalence of multidrug-resistant Pseudomonas aeruginosa strains in Ardabil. Methods: During 9 months, between July 2019 and March 2020, 50 strains of Pseudomonas aeruginosa were collected from different clinical specimens in four hospitals of Ardabil and the prevalence of MDR, XDR and PDR strains of Pseudomonas aeruginosa were evaluated. Antibiotic susceptibility testing was assessed using the disk diffusion method. Results: In the present study, the prevalence of MDR, XDR and PDR strains of Pseudomonas aeruginosa were 52%, 40% and 14%, respectively. Conclusion: Due to high prevalence of multidrug-resistant strains of Pseudomonas aeruginosa in Ardabil, continuous monitoring of the antibiotic resistance trend in clinical isolates in order to select the best medication is necessary.

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