title

یک بررسی ادبیات تاریخی در مورد نقش میدان خلفی تقویتی آگزیلا در پوشش غدد لنفاوی آگزیلا و توسعه لنف ادم به دنبال پرتودهی گره های لنف نود محیطی در سرطان پستان

افخمی اردکانی, مهدیه and غفاری, حامد and مردی, افروز and رفاهی, سهیلا (1400) یک بررسی ادبیات تاریخی در مورد نقش میدان خلفی تقویتی آگزیلا در پوشش غدد لنفاوی آگزیلا و توسعه لنف ادم به دنبال پرتودهی گره های لنف نود محیطی در سرطان پستان. Reports of Practical Oncology & Radiotherapy ــ 26 (4). pp. 635-346. شاپا 1507-1367

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Title

A historical literature review on the role of posterior axillary boost field in the axillary lymph node coverage and development of lymphedema following regional nodal irradiation in breast cancer

English Abstract

To elucidate whether (1) a posterior axillary boost (PAB) field is an optimal method to target axillary lymph nodes (LNs); and (2) the addition of a PAB increases the incidence of lymphedema, a systematic review was undertaken. A literature search was performed in the PubMed database. A total of 16 studies were evaluated. There were no randomized studies. Seven articles have investigated dosimetric aspects of a PAB. The remaining 9 articles have determined the effect of a PAB field on the risk of lymphedema. Only 2 of 9 articles have prospectively reported the impact of a PAB on the risk of lymphedema development. There are conflicting reports on the necessity of a PAB. The PAB field provides a good coverage of level I/II axillary LNs because these nodes are usually at a greater depth. The main concern regarding a PAB is that it produces a hot spot in the anterior region of the axilla. Planning studies optimized a traditional PAB field. Prospective studies and the vast majority of retrospective studies have reported the use of a PAB field does not result in increasing the risk of lymphedema development over supraclavicular-only field. The controversies in the incidence of lymphedema suggest that field design may be more important than field arrangement. A key factor regarding the use of a PAB is the depth of axillary LNs. The PAB field should not be used unless there is an absolute indication for its application. Clinicians should weigh lymphedema risk in individual patients against the limited benefit of a PAB, in particular after axillary dissection. The testing of the inclusion of upper arm lymphatics in the regional LN irradiation target volume, and universal methodology measuring lymphedema are all areas for possible future studies.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :مهدیه افخمی اردکانی
نویسنده مسئول :حامد غفاری
نویسنده :افروز مردی
نویسنده :سهیلا رفاهی
Additional Information:Indexed in: Scopus, ESCI, PubMed/PMC, Embase
کلیدواژه ها (انگلیسی):posterior axillary boost; breast cancer radiotherapy; axillary lymph node; regional nodal irradiation
Subjects:WH Hemic and Lymphatic System
WN Radiology . Diagnostic Imaging
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Medical Physics
ID Code:14234
Deposited By: Dr Soheila Refahi
Deposited On:02 Sep 1400 09:34
Last Modified:02 Sep 1400 09:34

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