مقایسه تاثیر پروبیوتیک با شربت کاراوی میکسچر در درمان کولیک

عنوان انگليسی

Comparison the effect of Probiotic with syrup-caraway-mixture in treatment of Infantile Colic

خلاصه انگلیسی

Background and Aim: Infantile colic is a relatively common behavioral syndrome in infancy. The main mechanism of colic is still unknown and no effective treatment is indicated for it. Recently a relation between colic-infected children and the microbial balance changes in their intestines has been reported. Accordingly, we decided to compare the effect of probiotic with the syrup-caraway-mixture on the colic. Materials and Methods: In this clinical trial study, 86 infants with colic. Data were collected by a checklist including duration of crying, severity of crying, crying frequency and complications of treatment which completed during the course of the treatment through the follow-up of the infants. Infants were randomly divided into two groups, based on random block design: probiotics (group one; 50) and syrup-caraway-mixture (group 2; 50). Collected data were analyzed by statistical methods in SPSS version 24. Results: The mean age of the patients was 30.58±14.18 days. Two groups were similar according to age, sex, birth weight, parental education level, history of atopy in family, history of colic in previous children and crying at presentation. There was no difference between groups based on the crying frequency, severity of crying and duration of crying on the 7th and 15th day. Also, the side effect of seventh and fifteenth days of treatment were similar between groups. Conclusion: Both probiotic and syrup-caraway-mixture are effective in the treatment of colic in infancy and had same side effects.

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