فرمولاسیون و ارزیابی پچ های دهانی بتامتازون با استفاده از روش چاپ سه بعدی

عنوان انگليسی

formulation and evaluation of Betamethasone oral patch prepared by 3D printing

خلاصه انگلیسی

There have been significant advances in the additive manufacturing techniques such as 3D printing over the past 30 years; so that they are considered the industrial revolution of the 21th century. these methods can be replaced for most of the traditional and conventional drug manufacturing methods. Attempts are now being made to provide individualized treatment based on individual differences. Individual pharmacotherapy or individual therapy is so effective in meeting the patients’ needs for treatment of the special diseases based on the individual anatomical and physiological differences, drug sensitivities, genetic polymorphisms, and the needed dosage. 3D printing has a high accuracy and it will soon be used for large scale production. By using 3D printing, unique products can be produced quickly and at low prices, so that these products cannot be produced by conventional methods.Aphthous ulcers has no specific cause. The patients affected by this condition usually suffer from an unfavorable feeling and pain for a long time. There is no effective drug for treatment of this complication. The products available in the treatment of oral lesions include soluble cocktails, topical pastes, mouthwashes and herbal drops that have a temporary effect and are washed off the site with saliva. . According to the collected data and the inefficiency of the manufactured drugs in improving the oral ulcers, we have used 3D printing to manufacture a drug delivery system proportional to the lesion size and site, the individuals’ anatomical and physiological differences, and their medical allergies which is last longer on lesion compared to existing products.

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