تظاهرات بالینی و یافته های آسیب شناختی توده های با منشاء عصبی در اردبیل، شمال غرب ایران

احمدآبادی, فرزاد and فتحی, افشین and آذین فر, پیمان and پورفرضی, فرهاد and صمدی خانقاه, علی (1400) تظاهرات بالینی و یافته های آسیب شناختی توده های با منشاء عصبی در اردبیل، شمال غرب ایران. در: eEANS 2021, Neurosurgery in Translation, October 3-7, 2021, Hamburg, Germany.



Clinical manifestations and pathologic findings of pediatric tumors with neuronal origin in Ardabil, Northwest of Iran

English Abstract

Background: Pediatric central nervous system (CNS) tumors are the second most common childhood malignancy after leukemias and the most common solid tumors. The incidence rate of childhood primary CNS tumors in the United States is approximately 5.67 per 100,000 person-years. Their comparative prevalence among other cancers, on one hand, the potentially threatening nature of involving a developing system, and quite vague symptoms particularly in younger children on the other hand make them more noteworthy. Methods: We prepared a case series study of space-occupying tumors with the neuronal origin in Bou’ Ali children’s center in Ardabil province, northwest of Iran. A total of 20 proven cases according to the revised WHO histological types since the foundation of our hospital for 10 years were collected. All the cases were then classified and analyzed for the relative frequency, the initial symptoms, and detailed location of tumors. The primary manifestations were placed in the 3 main categories: symptoms suggesting raised intracranial pressure, focal neurological deficits, and nonspecific ones. Evidence of abducent nerve palsy and hospitalization for chemotherapy adverse effects were the other instances. Results: The most frequent type of CNS tumors was optic gliomas, followed by medulloblastoma, and neuroblastoma besides 5 PNETs. We did not have accurate diagnoses for a brain and a spinal tumor for the parental dissent to biopsy. 8 of 10 intracranial tumors had revealed intracranial hypertension and all 6 cases of optic gliomas had signs of abducent nerve palsy. Cytopenia, pneumonia, and oral ulcers were the commonest causes of hospitalizations without chemotherapy. Conclusion: The relative frequency of our tumors corresponded to international reports. Moreover, symptoms due to intracranial hypertension and esotropia representing abducent palsy were predominant which warns carefully evaluating for a child with these signs or symptoms especially in the youngers who cannot probably communicate.

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده اول :فرزاد احمدآبادی
نویسنده :افشین فتحی
نویسنده :پیمان آذین فر
نویسنده :فرهاد پورفرضی
نویسنده مسئول :علی صمدی خانقاه
Subjects:QY Clinical Pathology
WL Nervous system
WS Pediatrics
WX Hospital and other health Facilities
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
ID Code:16113
Deposited By: علی صمدی
Deposited On:11 Jul 1401 10:32
Last Modified:11 Jul 1401 10:32

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