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سطوح NT-Pro-BNP در طی تست تنفس خود به خود و ارتباط آن بااکتوباسیون موفقیت آمیز در بیماران تحت تهویه مکانیکی در بخش مراقبت های ویژه

میکائیلی, هاله ، بیوک آقازاده, کاترین ، ناظمیه, مسعود ، متین, سمیه (1399) سطوح NT-Pro-BNP در طی تست تنفس خود به خود و ارتباط آن بااکتوباسیون موفقیت آمیز در بیماران تحت تهویه مکانیکی در بخش مراقبت های ویژه. Journal of Research in Clinical Medicine ــ 8 (45). ص.ص.1-4. شاپا 2717-0616

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آدرس اینترنتی رسمی : https://jrcm.tbzmed.ac.ir/Article/jrcm-31829


عنوان انگليسی

NT-Pro-BNP levels during spontaneous breathing test and its association with successful weaning in patients undergoing mechanical ventilation in the Intensive Care Unit

خلاصه انگلیسی

Introduction: Weaning of the patient is one of the important medical challenges. One of the most important causes of failure in weaning is cardiovascular disorders. NT-Pro-BNP is a serum marker for cardiac dysfunction. This study conducted to evaluate the level of NT-Pro-BNP during the spontaneous breathing test (SBT) in patients undergoing mechanical ventilation in ICU and its association with successful weaning. Methods: In this cross-sectional study, we enrolled 42 intubated patients who were admitted to the ICU ward of Imam Reza Hospital and were clinically weaned. After obtaining informed consent, SBT was started for the patient. One and a half hours after SBT onset, a venous blood sample was obtained and the patients were followed for SBT test success and the results were recorded. Patients were extubated in stabilized condition or continued mechanical ventilation if needed. Then Data were analyzed. Results: SBT was successful in 45.2% of patients. 54.8% of patients were male. The most common cause of hospitalization was COPD (35.7%). The mean age of patients with successful SBT was 67.53±6.14 years and in patients with unsuccessful SBT was 68.70±5.44 years. There was a significant difference between NT-Pro-BNP levels half an hour after SBT between two groups of patients with successful (7.15±31.18) and unsuccessful (59.61±196.51) SBT. NT-ProBNP changes before and half an hour after SBT in both groups were statistically significant. Conclusion: NT-Pro-BNP is a predictor criteria of success in weaning in patients and as the level of NT-Pro-BNP increases, the rate of failure in weaning increases.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :هاله میکائیلی
نویسنده مسئول :کاترین بیوک آقازاده
نویسنده :مسعود ناظمیه
نویسنده :سمیه متین
ضریب تاثیر و نمایه مجلات:Indexed in: PubMed/PMC
کلیدواژه ها (انگلیسی):NT-Pro-BNP, spontaneous breath test, Ventilator Weaning
موضوعات :WF سیستم تنفسی
بخش های دانشگاهی :دانشكده پزشكي > گروه داخلی ، قلب ، عفونی
کد شناسایی :16292
ارائه شده توسط : دکتر سمیه متین
ارائه شده در تاریخ :21 آبان 1401 10:26
آخرین تغییر :12 بهمن 1401 10:38

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