آندومتریوز در زنان نابارور درمان شده با ART و جراحی

عنوان انگليسی

ENDOMETRIOSIS RECURRENCE IN INFERTILE WOMEN TREATED BY ASSISTED REPRODUCTIVE TECHNOLOGY AND SURGERY

خلاصه انگلیسی

Endometriosis is a benign gynecologic disease which up to 30-50% of infertile women characterized by it1,2. Infertility treatments such as laparoscopic surgery and assisted reproductive technology (ART) increase the chance of conception in women with endometriosis. It is still not clear which treatment is more likely to result in endometriosis recurrence3. This abstract is prepared by searching the keywords of endometriosis recurrence, infertility, and assisted reproductive technologies in Google Scholar and PubMed databases. Based on moderate quality evidence, in vitro fertilization (IVF) does not increase the risk of endometriosis recurrence, albeit low quality evidence indicates intrauterine insemination (IUI) may increase the risk of endometriosis recurrence4. Furthermore, the risk of endometriosis recurrence is not associated with the number of IVF cycles and the responsiveness to ovarian hyperstimulation (OH)5. Additionally, the cumulative endometriosis recurrence rate is lower after OH for IVF than after lower-dose ovarian stimulation for suggesting that temporary exposure to high estradiol levels during OH for IVF is not a major risk factor for endometriosis recurrence in women treated with ART6. Moreover, there is no significant difference between the rate of endometriosis recurrence in infertile women treated by surgery and ART3. It seems that the risk of endometriosis recurrence is not soared by ART (especially IVF) or surgery and there is no necessary to do prophylactic surgery before ART treatment to prevent endometriosis recurrence.

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