مکمل کورکومین به عنوان یک درمان کمکی به تسکین شاخص های تن سنجی و گلیسمی کمک می کند: بررسی متا پژوهشی متاآنالیزها

عنوان انگليسی

Curcumin supplementation contributes to relieving anthropometric and glycemic indices, as an adjunct therapy: A meta-research review of meta-analyses

خلاصه انگلیسی

Background: Curcumin, a natural polyphenolic compound, can affect anthropometric and glycemic indices; however, the findings of existing meta-analyses are controversial. Study design: The current umbrella meta-analysis was performed among present systematic reviews and metaanalyses to investigate the effect of curcumin supplementation on anthropometric and glycemic indices. Methods: A comprehensive systematic search was performed on Embase, PubMed, WOS, Scopus, and Cochrane Library to obtain peer-reviewed papers published before 30/November/2021. meta-analysis was conducted using the random-effects model. Results: 12 meta-analyses were included in the current study. Our results have revealed that the curcumin supplementation can significantly decrease body mass index (BMI), body weight (BW), waist circumference (WC), fasting blood sugar (FBS), homeostasis model assessment-estimated insulin resistance (HOMA-IR), hemoglobin A1c (HbA1c), and insulin. Conclusion: These findings recommend curcumin supplementation as a favorable intervention to improve anthropometric and glycemic indices.

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