title

خطر ابتلا به سرطان سینه در زنان با شیفت کار شب

رفاهی, سهیلا and مردی, افروز and مشعوفی, مهرناز (1389) خطر ابتلا به سرطان سینه در زنان با شیفت کار شب. در: دوازدهمین همایش سالانه آسیب شناسی ایران ششمین همایش سالانه انجمن سرطان ایران , 26-28 آبان ماه 1389, دانشگاه علوم پزشکی تهران.

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Persian Abstract

Title

Risk of Breast Cancer in Women and working on night shifts

English Abstract

There is little information about the direct effect of night work on the risk of cancer. Melatonin, the “hormone of the darkness,” has only recently gained substantial attention from the scientific community with regard to its potential oncostatic actions and its possible effect on breast cancer risk. Melatonin serum levels in humans decrease when people are exposed to light at night. Suppressed serum melatonin levels might enhance tumor development. The evidence of a relation between melatonin and oncogenesis in humans is conflicting, but the majority of reports indicate protective action. Several mechanisms have been hypothesized to explain an association between melatonin and breast cancer. In this review article, we evaluate the relationship between night work, as a surrogate for light exposure at night, and breast cancer risk in women. We attempted to explain the slight differences in the association of shiftwork duration and breast cancer risk between premenopausal and postmenopausal women by examining whether the effects of shiftwork varied in specific subgroups

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده مسئول :سهیلا رفاهی
کلیدواژه ها (انگلیسی): breast-cancer-working night shifts
Subjects:WP Gynecology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Health Information Management
Faculty of Medicine > Department of Basic Sciences > Department of Medical Physics
Faculty of Health > Department of Public health
Faculty of Health > Department of Public health
Faculty of Health > Department of Public health
ID Code:1816
Deposited By: Dr Mehrnaz Mashoufi
Deposited On:01 Sep 1389 01:10
Last Modified:02 Apr 1393 04:49

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