ابراهیم اوغلی, رضا ، جنتی, علی ، قرایی, حجت اله ، آقایی, میرحسین (1402) الگوی مصرف چندداوریی در ایران: تحلیل جامع از بانک اطلاعاتی نسخه های تجویزی. Iranian Journal of Pharmaceutical Research ــ 21 (1). e131304. شاپا 1735-0328
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آدرس اینترنتی رسمی : https://brieflands.com/articles/ijpr-131304
عنوان انگليسی
Polypharmacy Pattern in Iran: A Comprehensive Analysis of a Large Prescription Database
خلاصه انگلیسی
Background: Polypharmacy is a significant patient safety concern. Objectives: This study aims to estimate the prevalence of polypharmacy, its continuity and associated factors, and common medication classes among a large outpatient population in East Azerbaijan province, Iran. Methods: A retrospective prescription data analysis was performed. The cohort included all ≥ 20 years old subjects with at least one prescription filled during the main three-month study period (2020 March 1 - 2020 May 31). Polypharmacy was defined as being exposed to more than four different medications during the main study period, and continuous polypharmacy was defined as being exposed to more than four medications during both the main study period and follow-up period (2020 October 1 - 2020 December 31). The frequency and prevalence of polypharmacy, along with predictive factors, were estimated. We performed multivariate logistic regression and estimated odds ratios (ORs) to investigate the risk factors for polypharmacy. Results: 307,820 patients included (mean age 49.8 years, 62.9% female, mean drug use 3.7 (SD = 2.6). Polypharmacy was observed in 28.3% (CI: 28.1 - 28.4), of which 36.6% experienced continuous polypharmacy. The odds of being exposed to polypharmacy increased with being female, increasing age, and exposure to chronic conditions. The groups of medications most utilized by polypharmacy patients were those indicated for gastro-esophageal reflux diseases, beta-blocking agents, antidepressants, blood glucose-lowering drugs, and antithrombotic agents. Conclusions: Strategies should be formulated to inform healthcare policymakers and providers about the magnitude of the polypharmacy phenomenon, associated factors, and the common medication classes involved.
نوع سند : | مقاله |
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زبان سند : | انگلیسی |
نویسنده اول : | رضا ابراهیم اوغلی |
نویسنده مسئول : | علی جنتی |
نویسنده : | حجت اله قرایی |
نویسنده : | میرحسین آقایی |
ضریب تاثیر و نمایه مجلات: | IF: 1.6 Indexed in: ISI , Scopus, PubMed/PMC |
کلیدواژه ها (انگلیسی): | Polypharmacy, Pharmacoepidemiology, Multimorbidity |
موضوعات : | QV فارماکولوژی > QV 754 داروسازی بالینی |
بخش های دانشگاهی : | آموزشکده عالی سلامت مشگین شهر |
کد شناسایی : | 18172 |
ارائه شده توسط : | دکتر میرحسین آقائی |
ارائه شده در تاریخ : | 29 فروردین 1403 12:19 |
آخرین تغییر : | 29 فروردین 1403 12:22 |
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