ارتباط سطح مت هموگلوبین با پروگنوز بیماران در مسمومیت با قرص برنج

مصطفی زاده, بابک ، فرزانه, اسماعیل ، افشاریان, تهمینه (1389) ارتباط سطح مت هموگلوبین با پروگنوز بیماران در مسمومیت با قرص برنج. در: کنگره بین المللی بررسی اثرات زنوبیوتیک ها, September 4 - 8, 2010, ترکیه-استامبول.

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عنوان انگليسي

Association of blood level of methemoglobin with clinical outcome of patients with aluminium phosphide poisoning

خلاصه انگلیسی

Background: Although methemoglobinemia following aluminum phosphide (AlP) intoxication has been reported, probable effect of blood level of methemoglobin (Met-Hb) on outcome of AlP intoxicated patients has not yet been investigated. This study aimed to evaluate this probable association. Methods: This prospective study was carried out at Loghman-Hakim poison hospital from April 2009 to August 2009 All patients aged >12 years who had ingested AlP and were admitted at the hospital were enrolled into the study. Using the co-oximetry, Met-Hb was measured at the time of admission and was repeated 24 hours later if the patient survived. Results: 48 AlP intoxicated cases including 24 males were enrolled into the study. Mean age of the patients was 25.5± 9.5 years. There was significant association between Met-Hb blood level which measured at the time of admission and mortality (2.4%± 7.1% in survivors versus 15.2%± 13.5% in non-survivors, P<0.001). The same association was found at the 2nd day of admission (2.9%±8.2% in survivors versus 26.5%±19.9% in non-survivors, P=0.02). Conclusions: The present study found an association between blood level of Met-Hb and mortality in AlP intoxicated cases. Whether prophylactic administration of vitamin C and methylene blue can improve outcome of AlP-intoxicated cases should be investigated in future investigations.

نوع سند :موضوع کنفرانس یا کارگاه (پوستر )
زبان سند : انگلیسی
نویسنده مسئول :بابک مصطفی زاده
کلید واژه ها:مت هموگلوبین،آلومینیوم فسفاید،مسمومیت،مرگ ومیر
کلید واژه ها (انگلیسی):Methemoglobinemia, Aluminum phosphide, Poisoning, Mortality
موضوعات :QV فارماکولوژی
بخش های دانشگاهی :دانشكده پزشكي > گروه داخلی ، قلب ، عفونی
کد شناسایی :1821
ارائه شده توسط : دکتر اسماعیل فرزانه
ارائه شده در تاریخ :15 آذر 1389 00:48
آخرین تغییر :01 اسفند 1391 14:12

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