بررسی سطح مت هموگلوبین در بیماران با مسمومیت قرص برنج وارتباط آن با مرگ ومیر آنها

مصطفی زاده, بابک and پژومند, عبدالکریم and فرزانه, اسماعیل (1389) بررسی سطح مت هموگلوبین در بیماران با مسمومیت قرص برنج وارتباط آن با مرگ ومیر آنها. Journal of medical toxicology ــ 6 . شاپا 1937-6995

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Blood Levels of Methemoglobin in Patients with Aluminum Phosphide Poisoning and its Correlation with Patient's Outcome

English Abstract

Although methemoglobinemia following aluminum phosphide (AlP) intoxication has been reported, probable effect of blood level of methemoglobin (Met-Hb) on outcome of AlP-poisoned patients has not yet been investigated. This study aimed to evaluate blood levels of methemoglobin in patients with AP intoxication and its correlation with patient’s outcome. This prospective study was carried out at the Loghman–Hakim poison hospital from April 2009 to August 2009. All patients aged >12 years who had ingested AlP and were admitted at the hospital were enrolled in the study. Using the co-oximetry, blood Met-Hb level was measured at the time of admission and 24 h later if the patient survived. Forty-eight patients with AlP intoxication including 24 males were evaluated. Mean age of the patients was 25.5±9.5 years. There was significant association between blood level of Met-Hb at the time of admission and mortality (2.4%±7.1% in survivors versus 15.2%±13.5% in non-survivors, P< 0.001). The same association was found at the 2nd day of admission (2.9%±8.2% in survivors versus 26.5%±19.9% in non-survivors, P=0.02). The present study found an association between blood level of Met-Hb and mortality in patients with AlP intoxication. Effect of administration of vitamin C and methylene blue on outcome of patients with AlP intoxication should be investigated in future studies.

Item Type:Article
زبان سند : انگلیسی
نویسنده مسئول :بابک مصطفی زاده
Additional Information:Abstracted/Indexed in: 1- PubMed/Medline, 2-EMBASE,SCOPUS, 3-Academic OneFile, Academic Search, Chemical Abstracts Service (CAS), Current Abstracts, EBSCO, Expanded Academic, Google Scholar, Health Reference Center Academic, IBIDS, OCLC, Summon by Serial Solutions
Uncontrolled Keywords:مت هموگلوبینمی ، فسفید آلومینیوم ، مسمومیت ، مرگ و میر
کلیدواژه ها (انگلیسی):Methemoglobinemia - Aluminum phosphide - Poisoning - Mortality
Subjects:WH Hemic and Lymphatic System
Divisions:Faculty of Medicine > Department of Internal Medicine , Cardiology , Infectious
ID Code:1874
Deposited By: Dr Esmaeil Farzaneh
Deposited On:10 Dec 1389 09:10
Last Modified:12 Nov 1391 09:47

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