ارزیابی اثرات افزودن کتامین به مرفین در pcia پس از جراحی ارتوپدی

اخوان اکبری, قدرت and ایمانی, فرناد and حیدریان, مجید and رحیم زاده, پوپک and شیرخانی, غلامرضا (1389) ارزیابی اثرات افزودن کتامین به مرفین در pcia پس از جراحی ارتوپدی. در: اولین کنگره بین المللی رژیونال آنستزی واینترونشنال درد ایران, 24 شهریور 1389, تهران-دانشگاه علوم پزشکی ایران-سالن همایشهای رازی.

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English Abstract

Background: Midazolam is the only clinically available water – soluble benzodiazepine has been reported to have an antinoceptive effect through neuroaxial pathway . We investigated systematically administrated midazolam on level and duration on motor and sensory block in spinal anesthesia with lidocaine. Methods: After obtaining the approval of the local Ethics committee and with written informed consent and under prospective double blind, randomized study, 36 adult ASA 1&2 patients who were scheduled for elective lower abdomen and lower extremity surgery under spinal anesthesia with 2 ml lidocain 5% were studied. Patients were allocated to two equal groups of receiving midazolam 0.03 mg/kg and fentanyl 1 µg/kg (group 2). Patients were evaluated for level and duration of sensory and motor block. Statistical analysis was performed using the SPSS soft ware. The T test, Chi- square and two way ANOVA were used to data analysis. Results: Sensory block level was T8 and T10 in group 1 and 2 respectively (P=0.02). The duration of sensory block was longer in group 1 (75.1 ± 28 min) than the group 2 (58.8 ± 23.3 min) , but this difference was not statistically significant (P=0.07). Duration of motor block was longer significantly (P=0.01) in group 1 (82.9 ± 27.3 min) than in group 2 (59.1 ± 26.5 min). Conclusion: Intravenous midazolam can improve the level of sensory block and the duration of motor block in spinal anesthesia without farther increasing the preoperatively complications. Key Word: Spinal anesthesia, midazolam, sensory block, motor block .

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده مسئول :قدرت اخوان اکبری
کلیدواژه ها (انگلیسی):PCA , Morphine , ketamine
Subjects:QV pharmacology
WO Surgery
Divisions:Faculty of Medicine > Department of Anesthesiology , Obstetrics & Gynecology
ID Code:2073
Deposited By: Dr Godrat Akhavanakbari
Deposited On:26 Dec 1389 11:41
Last Modified:10 Jan 1393 09:39

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