title

اندازه گیری غلظت سرمی نیتریک اکسید سنتاز اندوتلیومی در افراد مبتلا به هلیکوباکتر پیلوری

امانی, مجتبی and اتحاد, غلامحسین and افشار قهرمانی, فیروزه (1390) اندازه گیری غلظت سرمی نیتریک اکسید سنتاز اندوتلیومی در افراد مبتلا به هلیکوباکتر پیلوری. در: Fifth Ditan International Conference on Infectious Diseases, 13-17 جولای 2011, Beijing, China.

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Title

Evaluation of serum concentration of eothelium nitric oxide synthase in Helicobacter pylori positive people

English Abstract

Objectives: Endothelium nitric oxide synthase (eNOS) is a type of enzyme which produces a endogenous factor called nitric oxide. NO plays important role in progress of euplastic diseases. In chronic gastritis induced by Helicobacter pylori, the production of NO enhances and damages DNA. The aim of present study is to evaluate eNOS concentration in serum of healthy people and those infected by HP. Methods: The serums and stools of 84 voluntaries were collected which %58.3 of them were women. HP antigen in stool samples and serum concentration of eNOS were determined using proper ELISA kits. Obtained data were analyzed using Excell software. Results: 16.6%, 29.76% and 53.57% of collected samples were equivocal, HP negative and positive respectively. Comparison of serums concentration of eNOS showed that there is no significant change among these three groups. Discussion: As mentioned in results the eNOS serums concentration shows no significant change in HP positive and negative groups. Albeit the other studies showed the significant increase in serum concentration of HP positive patient, this contradiction may arise from race and HP pathogenic slands such as VacA and CagA differences. We propose to conduct a similar study in Ardabil with special regard to pathogenic islands

Item Type:Conference or Workshop Item (Speech)
زبان سند : انگلیسی
نویسنده مسئول :مجتبی امانی
Uncontrolled Keywords:سرطان معده ، هلیکوباکتر پیلوری ، تیتریک اکسید سنتاز اندوتلیومی
کلیدواژه ها (انگلیسی):eNOS , Helicobacter Pylori , Gastric Cancer
Subjects:QU Biochemistry
QW Microbiology and Immunology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Biophysics
Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:2522
Deposited By: Dr Mojtaba Amani
Deposited On:17 May 1390 10:20
Last Modified:21 Jan 1393 09:28

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  • اندازه گیری غلظت سرمی نیتریک اکسید سنتاز اندوتلیومی در افراد مبتلا به هلیکوباکتر پیلوری. (deposited 17 May 1390 10:20) [Currently Displayed]

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