محمودیان, مسعود and فلاحتی, م. and فیضی, مهرداد and بهلولی, شهاب and صوفیان, ن.د. (1390) مطالعه سمیت مبودیپین و دیبودیپین، دو مسدد جدید کانال کلسیمی بر روی ساکرومیسس سرویسس و هپاتوسیت های ایزوله موش صحرایی (rat) به شکل آزمایشگاهی. International Journal of Pharmacy and Pharmaceutical Sciences ــ 3 (3). pp. 204-207. شاپا 0975-1491
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Official URL: http://www.ijppsjournal.com/Vol3Issue3.htm
Title
TOXICOLOGICAL STUDY OF MEBUDIPINE AND DIBUDINE, TWO NEW CALCIUMCHANNEL BLOCKERS, IN SACCHAROMYCES CERVISES AND ISOLATED RAT HEPATOCYTES CELLS INVITRO
English Abstract
Mebudipine and Dibudipine are two new calcium antagosists used in laboratory animals. Toxicological testing were evaluated in cultured mouse cells in‐vitro and on growth yeast cells . It is shown that in these two system it is safe and no toxicological effect has been shown. Therefore, it is concluded that considering effect of mebudipne on yeast cells, heptocytes cells in‐vitro, and reported effect on salmonella11, it can be said that is drug is safe and can be used in humans.
| Item Type: | Article |
|---|---|
| زبان سند : | انگلیسی |
| نویسنده مسئول : | مسعود محمودیان |
| Additional Information: | Impact factor- 0.38 (2010) Abstracting and Indexing: 1- Medline, Pubmed, Pubmed Central 2- Scopus, EMBASE,Chemical Abstracts, 3-Google Scholar, Elsevier, EBSCO, SCI mago (SJR), CAS, CASSI (American Chemical Society), Directory of Open Access Journal (DOAJ), Index Copernicus, ICAAP, Scientific commons, PSOAR, Open-J-Gate. |
| کلیدواژه ها (انگلیسی): | Mebudipine, Dibudipinedihydropyridine, Calcium antagonists, Saccharomyces cerevisiae |
| Subjects: | QV pharmacology |
| Divisions: | Faculty of Medicine > Department of Basic Sciences > Department of Pharmacology |
| ID Code: | 2860 |
| Deposited By: | Dr Shahab Bohlooli |
| Deposited On: | 27 Sep 1390 12:58 |
| Last Modified: | 07 Nov 1391 12:45 |
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