اثر اندانسترون و پتدین در پیشگیری از لرز بعداز عمل به دنبال بیهوشی عمومی

انتظاری, مسعود and عیسی زاده فر, خاطره and محمدیان اردی, علی and خوشباطن, منوچهر (1390) اثر اندانسترون و پتدین در پیشگیری از لرز بعداز عمل به دنبال بیهوشی عمومی. Middle East Journal of Anesthesiology ــ 1 (21). pp. 67-70. شاپا 0544-0440

Text - Published Version

Official URL: http://www.meja.aub.edu.lb/21_1.html


Ondansetron and meperidine prevent postoperative shivering after general anesthesia

English Abstract

Postoperative shivering is one of the common problems following general anesthesia and may lead to multiple complications. The aim of this study was to examine the preventive effects of Ondansetron and Meperidine on postoperative shivering. This randomized placebo-controlled double blind clinical trial included 90 patients scheduled for elective gynecologic operations, randomly divided to three groups. Ondansetron (4 mg), Meperidine (0.4 mg/kg) and 2 cc normal saline (as a control group) were administered immediately before the induction of anesthesia. Anesthesia induced equivalently for all. Patients were observed in terms of vital signs, side effects and shivering. Postoperative shivering was observed in 13.3% of patients in Ondansetron group and 20% of Meperidine group, significantly lower than the controls (50%). The reduction of core and dermal temperature during the anesthesia and recovery, changes in systolic and diastolic blood pressure and heart rate were similar in all three groups. The incidence of nausea was similar among the three groups of study while vomiting occurred in 6.7% of the Meperidine group and 3.3% of the controls but none in the patients receiving Ondansetron. Ondansetron can effectively reduce post operative shivering.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :مسعود انتظاری
نویسنده مسئول :منوچهر خوشباطن
Additional Information:Indexed In: 1- MEDLINE - PubMed 3-Index medicus
کلیدواژه ها (انگلیسی):General anesthesia , Postoperative shivering , Ondansetron
Subjects:QV pharmacology
WO Surgery
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
Faculty of Medicine > Department of Anesthesiology , Obstetrics & Gynecology
ID Code:2912
Deposited By: Dr Masood Entezariasl
Deposited On:26 Sep 1390 13:55
Last Modified:10 Dec 1391 11:26

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