سروتیپ های کپسولی و الگوی مقاومت آنتی بیوتیکی استرپتوکوک های گروه B جداشده از زنان باردار اردبیل،ایران

جنتی, الهام and روشنی, مرضیه and ارزنلو, محسن and حبیب زاده, شهرام and رحیمی, گیتی and شاپوری, رضا (1391) سروتیپ های کپسولی و الگوی مقاومت آنتی بیوتیکی استرپتوکوک های گروه B جداشده از زنان باردار اردبیل،ایران. Iranian Journal of Microbiology ــ 4 (3). pp. 130-135. شاپا 2008-3289

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Official URL: http://ijm.tums.ac.ir/index.php/ijm/article/view/5...


Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran

English Abstract

Background and Objectives: Group B Streptococci (GBS) is a major cause of neonatal and maternal infections. The aim of this study was to determine the serotype distribution and antibiotic resistance profile of GBS strains isolated from pregnant women in Ardabil. Materials and Methods: Antibiotic resistance of 56 GBS isolates was investigated using E-test strips and disk-diffusion method. Serotyping was performed using capsular antiserum. Results: The results of MIC tests showed all isolates were susceptible to ampicillin, vancomycin and penicillin. One isolate (1.7%) showed reduced susceptibility pattern to penicillin (MIC; 0.25 μg/ml). There were 3 (5.3%) isolates semi-sensitive (0.25-1 μg/ml) to erythromycin (2; 0.5 μg/ml and 1; 0.38 μg/ml) and 2 (3.5%) isolates to clindamycin (1; 0.5 μg/ml, 1; 0.38 μg/ml). Additionally, 2 (3.5%) isolates were resistant to clindamycin (1; 16 μg/ml, 1; 2 μg/ml). According to the disk diffusion test, 47 (83.9%), 8 (14.2%) and 7 (12.5%) isolates were resistant to Co-trimoxazole, ciprofloxacin and ceftriaxone respectively. Serotypes V (19.6%), II (12.5%) and IV (12.5%) were the most frequent followed by serotypes III (10.7%) and VI (10.7%), Ib (8.9%), Ia (7/1%), VII (5/3%) and VIII (5/3%); 7.1% of strains were nontypeable. Conclusions: In this study, most isolates were sensitive to common antibiotics, but increased resistance to other antibiotics indicates the importance of monitoring of antibiotic resistance in group B streptococci over time.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :الهام جنتی
نویسنده مسئول :محسن ارزنلو
Additional Information:Indexed in : PubMed/PMC,Scopus, Embase, Index Copernicus, Google Scholars, Iran Medex, Magiran, SID , ISC.
Uncontrolled Keywords:استرپتوکوک های گروه، سروتیپ، مقاومت آنتی بیوتیکی
کلیدواژه ها (انگلیسی):Antibiotic resistance, Group B Streptococci, Serotype
Subjects:QW Microbiology and Immunology
WQ Obstetrics
Divisions:Faculty of Medicine > Department of Anesthesiology , Obstetrics & Gynecology
Faculty of Medicine > Department of Internal Medicine , Cardiology , Infectious
Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:3527
Deposited By: Dr Mohsen Arzanlou
Deposited On:02 Jul 1391 08:50
Last Modified:20 Feb 1399 16:22

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