تاثیر مکمل اسیدهای چرب امگا سه بر وضعیت تغذیه بیماران مبتلا به سرطان معده تحت شیمی درمانی

نعمتی, علی and نچواک, سیدمصطفی and جعفریان, کوروش and فیضی, ایرج (1393) تاثیر مکمل اسیدهای چرب امگا سه بر وضعیت تغذیه بیماران مبتلا به سرطان معده تحت شیمی درمانی. Journal of Nutritional Sciences and Dietetics ــ 1 (1). pp. 2-8. شاپا 2383-4218

Text - Published Version

Official URL: http://jnsd.tums.ac.ir/index.php/jnsd/article/view...


Effect of omega-3 fatty acid supplementation on nutritional status in patients with gastric cancer during chemotherapy

English Abstract

Background: Although some studies have shown positive effects of omega-3 fattyacid supplementation on nutritional status of cancer patients undergoing differenttreatments, there is no consistency in results. The aim of this study was to examinethe effects of omega-3 fatty acid on the nutritional status of gastric cancer patientsduring the course of chemotherapy. Methods: In a double-blind clinical trial, 30 adult patients with gastric cancerreceiving chemotherapy were randomized into a supplement and a placebo groupsand given daily, for 6 weeks, a 3-g omega-3 fatty acid supplement (containing 1.8geicosapentaeonic plus 1.2g docosahexaenoic acid) and oral paraffin, respectively.Anthropometric data was collected and nutritional status assessed at the beginning,at week 4 and at the end of week 6. The data were analyzed using repeatedmeasures ANOVA and independent sample t-test. Results: The findings indicated that omega-3 fatty acid supplementation increasedbody weight, mean daily intake of energy and macronutrients, serum levels oftransferrin and albumin at the end of the 6-week period significantly (p<0.05). Allthese variables decreased in the placebo group (p<0.05). The increases in bodyweight, energy and carbohydrate intakes, and serum levels of albumin in thesupplement group were time-dependent (p<0.05). Conclusion: The results of present study showed that omega-3 fatty acidsupplementation can improve nutritional status in patients with gastric cancerduring the course of chemotherapy. We recommend using omega-3 fatty acidsupplement in patients with gastric cancer during chemotherapy.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :علی نعمتی
نویسنده :سیدمصطفی نچواک
نویسنده :کوروش جعفریان
نویسنده مسئول :ایرج فیضی
Additional Information:Indexing & Abstracting Directory of Research Journal Indexing (DRJI), Google Scholar,
کلیدواژه ها (انگلیسی):Omega 3 fatty acid, Weight, Nutrition, Gastric cancer, Chemotherapy
Subjects:WD Nutrition Disease and metabolic diseases
WI Digestive System
WN Radiology . Diagnostic Imaging
Divisions:Faculty of Medicine > Department of Surgery
Faculty of Medicine > Department of Basic Sciences > Department of Nutrition
ID Code:3635
Deposited By: Dr Ali Nemati
Deposited On:16 Jan 1394 06:51
Last Modified:01 Feb 1394 03:24

Repository Staff Only: item control page

Document Downloads

More statistics for this item...