title

miRNA

حسینی اصل, سید سعید (1392) miRNA. [Teaching Resource]

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Title

miRNA

English Abstract

MicroRNAs (miRNAs) are small noncoding RNAs which enhance the cleavage or translational repression of specific mRNA with recognition site(s) in the 3’-untranslated region (3’UTR). •The biogenesis of miRNA is controlled by two RNase-dependent processing steps that converts a long primary transcript into a mature ~20 nt miRNA. • The mature miRNA are released and then loaded onto the miRNA-induced silencing complex (miRISC), which acts as a guiding strand to recognize specific mRNA targets. 3

Item Type:Teaching Resource
زبان سند : انگلیسی
نویسنده :سید سعید حسینی اصل
کلیدواژه ها (انگلیسی):miRNA , cancer , tumorigenesis , metastasis
Subjects:QU Biochemistry
QZ Pathology
WB Practice of Medicine
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Genetics
ID Code:4263
Deposited By: Dr S Saied Hosseini-Asl
Deposited On:20 Mar 1392 12:25
Last Modified:20 Mar 1392 12:26

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