مقایسه اثرات رمی فنتانیل و آلفنتانیل بر فشار داخل چشمی در بیماران تحت عمل جراحی کاتارکت

اخوان اکبری, قدرت ، انتظاری, مسعود ، اوجاقی, حبیب ، عیسی زاده فر, خاطره (1392) مقایسه اثرات رمی فنتانیل و آلفنتانیل بر فشار داخل چشمی در بیماران تحت عمل جراحی کاتارکت. Saudi Journal of Anaesthesia ــ 7 (2). ص.ص.160-164. شاپا 1658-354X

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آدرس اینترنتی رسمی : http://www.saudija.org/article.asp?issn=1658-354X;...

عنوان انگليسي

Comparison of the effects of remifentanil and alfentanil on intraocular pressure in cataract surgery

خلاصه انگلیسی

Background: Anesthesia for ophthalmic surgery requires management of intraocular pressure (IOP) during perioperative period. In an open eye, in conditions such as after traumatic injury or during cataract surgery, IOP increase can lead to permanent vision loss. Administration of narcotics concomitant with anesthetics has the ability to reduce this increase of IOP. This clinical trial aims to compare the efficacy of remifentanil and alfentanil in preventing an increase in IOP after administration of succinylcholine, intubation and during anesthesia. Methods: This double-blind clinical trial was conducted on 50 patients undergoing elective general surgery for cataracts. Patients were randomly divided into two groups. Alfentanil (20 μg/kg in 30 s) for group 1 and remifentanil (1 μg/kg in 30 s) for group 2 were injected before induction of anesthesia, and 0.5 μg/kg/min alfentanil for group 1 and 0.1 μg/kg/min remifentanil for group 2 were infused during the anesthesia. Systolic and diastolic blood pressure, heart rate, and IOP from normal eye were measured before the induction, after administration of thiopental and succinylcholine, after tracheal intubation, and 2 min later, and were repeated in 2-min intervals until the end of operation. Results: IOP decreased after injection of anesthetics and remained lower all through the operation in both groups, but IOP decreased after injection of succinylcholine in remifentanil group while it increased in alfentanil group (P<0.05). Conclusions: Results of this study indicate benefits of both remifentanil and alfentanil in managing IOP after induction and during anesthesia. It seems that remifentanil is better than alfentanil in controlling the IOP after injection of succinylcholine.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :قدرت اخوان اکبری
نویسنده مسئول :مسعود انتظاری
نویسنده :حبیب اوجاقی
نویسنده :خاطره عیسی زاده فر
اطلاعات اضافی :Indexing : PubMed, Pubmed Central, SCOPUS, DOAJ, EBSCO Publishing's Electronic Databases, EMR Index Medicus, Google Scholar, Index Copernicus, ProQuest, Scimago Journal Ranking, SIIC databases, Summon by Serial Solutions, Ulrich's International Periodical Directory
کلید واژه ها:آلفنتانیل ، بیهوشی ، جراحی کاتاراکت ، فشار داخل چشمی ، رمی فنتانیل
کلید واژه ها (انگلیسی):Alfentanil , anesthesia , cataract surgery , intraocular pressure , remifentanil
موضوعات :QV فارماکولوژی
WO جراحی
WW چشم پزشکی
بخش های دانشگاهی :دانشكده پزشكي > گروه بیهوشی، زنان و زایمان
دانشكده پزشكي > گروه جراحی
کد شناسایی :4317
ارائه شده توسط : دکتر مسعود انتظاری اصل
ارائه شده در تاریخ :06 تیر 1392 08:10
آخرین تغییر :30 فروردین 1393 13:05

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