مقایسه اثرات رمی فنتانیل و آلفنتانیل بر فشار داخل چشمی در بیماران تحت عمل جراحی کاتارکت

اخوان اکبری, قدرت and انتظاری, مسعود and اوجاقی, حبیب and عیسی زاده فر, خاطره (1392) مقایسه اثرات رمی فنتانیل و آلفنتانیل بر فشار داخل چشمی در بیماران تحت عمل جراحی کاتارکت. Saudi Journal of Anaesthesia ــ 7 (2). pp. 160-164. شاپا 1658-354X

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Official URL: http://www.saudija.org/article.asp?issn=1658-354X;...


Comparison of the effects of remifentanil and alfentanil on intraocular pressure in cataract surgery

English Abstract

Background: Anesthesia for ophthalmic surgery requires management of intraocular pressure (IOP) during perioperative period. In an open eye, in conditions such as after traumatic injury or during cataract surgery, IOP increase can lead to permanent vision loss. Administration of narcotics concomitant with anesthetics has the ability to reduce this increase of IOP. This clinical trial aims to compare the efficacy of remifentanil and alfentanil in preventing an increase in IOP after administration of succinylcholine, intubation and during anesthesia. Methods: This double-blind clinical trial was conducted on 50 patients undergoing elective general surgery for cataracts. Patients were randomly divided into two groups. Alfentanil (20 μg/kg in 30 s) for group 1 and remifentanil (1 μg/kg in 30 s) for group 2 were injected before induction of anesthesia, and 0.5 μg/kg/min alfentanil for group 1 and 0.1 μg/kg/min remifentanil for group 2 were infused during the anesthesia. Systolic and diastolic blood pressure, heart rate, and IOP from normal eye were measured before the induction, after administration of thiopental and succinylcholine, after tracheal intubation, and 2 min later, and were repeated in 2-min intervals until the end of operation. Results: IOP decreased after injection of anesthetics and remained lower all through the operation in both groups, but IOP decreased after injection of succinylcholine in remifentanil group while it increased in alfentanil group (P<0.05). Conclusions: Results of this study indicate benefits of both remifentanil and alfentanil in managing IOP after induction and during anesthesia. It seems that remifentanil is better than alfentanil in controlling the IOP after injection of succinylcholine.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :قدرت اخوان اکبری
نویسنده مسئول :مسعود انتظاری
نویسنده :حبیب اوجاقی
نویسنده :خاطره عیسی زاده فر
Additional Information:Indexing : SCOPUS, DOAJ, Google Scholar, Index Copernicus, ProQuest,
Uncontrolled Keywords:آلفنتانیل ، بیهوشی ، جراحی کاتاراکت ، فشار داخل چشمی ، رمی فنتانیل
کلیدواژه ها (انگلیسی):Alfentanil , anesthesia , cataract surgery , intraocular pressure , remifentanil
Subjects:QV pharmacology
WO Surgery
WW Ophthalmology
Divisions:Faculty of Medicine > Department of Anesthesiology , Obstetrics & Gynecology
Faculty of Medicine > Department of Surgery
ID Code:4317
Deposited By: Dr Masood Entezariasl
Deposited On:06 Apr 1392 08:10
Last Modified:03 Sep 1398 14:38

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