بررسی اپیدمیولوژی مولکولی استافیلوکوکوس اورئوس های واجد ژن ACME_arcA در افراد ناقل سالم

غزنوی راد, احسان الله and رضازاده, محسن and آموزنده, علیرضا and ژاپونی نژاد, علیرضا and کاظمیان, حمید and طبیب نژاد, مهسا and برناسی, حبیب and فرد موسوی, نسیمه and بنیادی, مهتاب and طاهری, نونا and اکبری, مجید (1391) بررسی اپیدمیولوژی مولکولی استافیلوکوکوس اورئوس های واجد ژن ACME_arcA در افراد ناقل سالم. در: The 13th Iranian & The Second International Congress of Microbiology, July 14 – 16, 2012, Ardabil - Iran.

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Official URL: http://congress.arums.ac.ir/index.php/IICM/5/sched...


Molecular Epidemiology of Staphylococcus aureus Carriage ACME-arcA Gene in Healthy Carrier

English Abstract

Background & Objectives: Staphylococcus aureus continues to be an important human pathogen in both healthcare and community settings. The arc gene cluster within the arginine catabolic mobile element ACME may has function as a virulence or strain survival factor. This study aimed to determine molecular epidemiology and prevalence of the ACME-associated arcA gene among S.aureus isolated from healthy student of Arak University of Medical Sciences. Methods:From the 568 nasal swap specimens , 82 S.aureus isolated by S. aureus–specific isolation procedures. Isolates thatcarriage ACME-arcA gene were identified by PCR, as well as PCR for determination ofSingle-locus spa sequence typing was carried out, then Data were analysed using Ridom StaphType software. Results: Among 82 S.aureus isolates, 11 (13.4%) were positive for arcA gene. Strain with spa type t660 was the only Methicillin-resistant Staphylococcus aureus (MRSA) and spa type t1149, t074, t790, t002, t021, t 084, t4892, t3204, t701(two isolates) were known as Methicillin-susceptible Staphylococcus aureus (MSSA). Conclusion:The detection of ACME-arcA in diverse S.aureus types highlights the mobility of the elements encoding ACME-arcA genes.The diversity of strain types among ACME-arcA-encoding S.aureus is a cause for public-health concern and demands continued surveillance and close monitoring.

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده مسئول :احسان الله غزنوی راد
کلیدواژه ها (انگلیسی):Staphylococcus aureus ; Arginine ; ACME ; ArcA Gene ; Ridom StaphType Software
Subjects:QW Microbiology and Immunology
QZ Pathology
Divisions:Vice Chancellor for Research and Technology > Deputy for Research and Technology management and Medical Information > University of Management Conferences and Congresses
ID Code:4562
Deposited By: MS Soghra Golmaghani
Deposited On:05 Jun 1392 12:24
Last Modified:26 Jun 1392 08:02

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