اهميت كلينيكي و بررسي حساسيت دارويي در جنس آئروكوكوس

Title

Clinical Significance And Antimicrobial Susceptibility of Aerococcus Spp

English Abstract

Background & Objectives: Aerococci are gram positive cocci, α-hemolytic. They are resemble those of enterococcus and viridians streptococcus. Genus Aerococcus contain five species: A. viridians, A. urinae, A. sanguinicola, A. christensenii, A. urinaehominis, that are found in the environment, usually in water, dust, vegetation and meat product. Aerococci have been isolated from patients with a number of clinical conditions, including endocarditis, bacteremia, meningitis, septic arteritis, wound and urinary tract infection.The aim of this study was to determine frequency of Aerococci in uti. Methods: 80 isolates of non-enterococcal streptococcal species obtained from urine culture. All strain were characterized using phenotypic approach: catalase, hemolysis gram staining from thioglycolate, growth on BEM, 6.5% NaCl, hippurate hydrolysis, susceptibility to vancomycin, VP, ONPG and susceptibility to antimicrobial agents. Results: between March 2010 and 2011, 3 cases (3.75%) Aerococci were recovered from uti. Although molecular Methods needs for confirmation, but it seems one strain was A. urinea and 2 A. viridians and A. sanguincola. All species were susceptible to Amoxycillin, Cephalosporins, Penicillin, Ciprofloxacin. A. urinae were resistant to Co-trimoxazole. Conclusion: Infection usually occur in patients with underlying disease in this study all patients were men > 50 years old. One had kidney graft, one, chronic prostitis and one uti. The identification and treatment of this bacteria should be noted.

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