بررسی فراوانی ناقلین بینی استافیلوکوکو اورئوس و تعیین الگوی مقاومت آنت بیوتیکی آن در بین پرسنل بیمارستان های شیراز

کاظمی, اکبر and سعادت, ساره and صلح جو, کاوس and نوروزنژاد, محمدجواد and روحی جهرمی, ریحانه (1391) بررسی فراوانی ناقلین بینی استافیلوکوکو اورئوس و تعیین الگوی مقاومت آنت بیوتیکی آن در بین پرسنل بیمارستان های شیراز. در: The 13th Iranian & The Second International Congress of Microbiology, July 14 – 16, 2012, Ardabil - Iran.

Text - Published Version


Antibiotic Resistance of Staphylococcus aureus Strains Isolated From Nasal of Carriage Persons in Shiraz Hospitals

English Abstract

Background & Objectives: Staphylococcus aureus is one of the most common causes of nosocomial infections. In many cases the bacterium is transmitted to patients via nasal carrier healthcare providers or hospital environment. Colonized healthcare providers are generally asymptomatic, but create a potential reservoir of infection for susceptible patients. The aim of this study was determination of antibiotic susceptibility to S.aureus isolated from personals of Shiraz hospitals. Methods: In this cross-sectional study nasal swabs were collected from 566 personals in Shiraz Hospitals (Chamran, Zeynabiye, MRI and Shahid Faghihi) in different wards, and examinated for detection of staphylococci strains. After identification of Staphylococcus aureus by biochemical and microbiological tests, antibiotic resistance pateern of isolates were determinate by disk diffusion Methods according to CLSI recommendations. Minimum inhibitory concentration (MIC) values for vancomycin and ticoplanin were assayed by E-test methods (Liofilechem, Itly). Results: In this investigation, 90 persons of staff (16%) were carrier Staphylococcus aureus in the nose. In that, 72% of them were health care workers and 28% of service personals. Antibiotic sensitivity in carriers was estimated as follows: vancomycin (97%), teicoplanin (97%), linezolid (97%), Quinupristin-Dalfopristin (97%), ciprofloxacin (95%), rifampin (93%), clindamycin (87%), methicillin (87%), erythromycin (81%), tetracycline (16%), amoxicillin (15%),penicillin (13%), ampicillin (8%). Form 12 MRSA strains, 2 strains (2%) were resistance to vancomycin (MIC≥16 µg/ml) and teicoplanin (MIC≥32 µg/ml). Conclusion: As 16% of personals in this study were carriers of Staphylococcus aureus and these isolates were resistant to most common antibiotics and these personals are in close contact with patients, we recommend that they should be examined for antibiotic resistant and treated periodically.

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده مسئول :اکبر کاظمی
کلیدواژه ها (انگلیسی):Staphylococcu aureus ; Carriage ; Hospital Personal ; Antibiotic Resistance
Subjects:QW Microbiology and Immunology
WB Practice of Medicine
WF Respiratory System
Divisions:Vice Chancellor for Research and Technology > Deputy for Research and Technology management and Medical Information > University of Management Conferences and Congresses
ID Code:4592
Deposited By: MS Soghra Golmaghani
Deposited On:09 Jun 1392 08:05
Last Modified:09 Jun 1392 08:05

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