مقاومت گونه های ضد میکروبی جدا شده از کودکان بیمار

رنجبر, رضا and میرسعید قاضی, فرزانه (1391) مقاومت گونه های ضد میکروبی جدا شده از کودکان بیمار. در: The 13th Iranian & The Second International Congress of Microbiology, July 14 – 16, 2012, Ardabil - Iran.

Text - Published Version

Official URL: http://congress.arums.ac.ir/index.php/IICM/5/sched...


Antimicrobial Resistance and ERIC PCR Patterns of Shigella sonnei Strains Isolated from Pediatric Patients in Tehran, Iran (2008-2010)

English Abstract

Background & Objectives: Shigella sonnei is considered as a major cause of diarrheal disease in both developing and developed countries. Iran is one of the endemic areas of shigellosis. The present study was undertaken to investigate the antibiotic susceptibility and genetic relatedness of S. sonnei strains isolated from pediatric patients in Tehran, Iran. Methods: The study included all S. sonnei strains isolated from pediatric patients with diarrhea who were admitted to several hospitals in Tehran, Iran, during 2008-2010. Shigella spp. strains were recovered from patients using standard microbiological methods. S. sonnei strains were further studied by antimicrobial susceptibility testing and Enterobacterial Repetitive Intergenic Consensus (ERIC) - PCR analysis. Results: Eighty nine Shigella isolates were isolated. S. sonnei was themost prevalent Shigella species (60.7%) followed by, S. flexneri (31.5%). Eleven antimicrobial resistance patterns (R1-R11) were identified among S. sonnei isolates. The majority of the strains were resistant to trimethoprim-sulfamethoxazole, tetracycline and streptomycin. All isolates were susceptible to ciprofloxacin, ceftizoxime and chloramphenicol. All strains were typable by ERIC-PCR. Five ERIC-PCR patterns (E1-E5) were found among S. sonnei isolates; however the half of the isolates was clustered in E4 pattern. Conclusion: We found the antibiotic resistance rates are increasing among S. sonnei strains. As reported in recent previous studies, our finding also indicated that a predominant clone or limited clones of S. sonnei are responsible for shigellosis caused by this Shigella species in pediatric patients in Tehran, Iran.

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده مسئول :رضا رنجبر
کلیدواژه ها (انگلیسی):Shigella sonnei ; Antibiotic Resistance ; ERIC-PCR
Subjects:QW Microbiology and Immunology
WS Pediatrics
Divisions:Vice Chancellor for Research and Technology > Deputy for Research and Technology management and Medical Information > University of Management Conferences and Congresses
ID Code:4600
Deposited By: MS Soghra Golmaghani
Deposited On:10 Jun 1392 09:21
Last Modified:10 Jun 1392 09:21

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