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مقاومت گونه های ضد میکروبی جدا شده از کودکان بیمار

رنجبر, رضا ، میرسعید قاضی, فرزانه (1391) مقاومت گونه های ضد میکروبی جدا شده از کودکان بیمار. در: The 13th Iranian & The Second International Congress of Microbiology, July 14 – 16, 2012, Ardabil - Iran.

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آدرس اینترنتی رسمی : http://congress.arums.ac.ir/index.php/IICM/5/sched...


عنوان انگليسي

Antimicrobial Resistance and ERIC PCR Patterns of Shigella sonnei Strains Isolated from Pediatric Patients in Tehran, Iran (2008-2010)

خلاصه انگلیسی

Background & Objectives: Shigella sonnei is considered as a major cause of diarrheal disease in both developing and developed countries. Iran is one of the endemic areas of shigellosis. The present study was undertaken to investigate the antibiotic susceptibility and genetic relatedness of S. sonnei strains isolated from pediatric patients in Tehran, Iran. Methods: The study included all S. sonnei strains isolated from pediatric patients with diarrhea who were admitted to several hospitals in Tehran, Iran, during 2008-2010. Shigella spp. strains were recovered from patients using standard microbiological methods. S. sonnei strains were further studied by antimicrobial susceptibility testing and Enterobacterial Repetitive Intergenic Consensus (ERIC) - PCR analysis. Results: Eighty nine Shigella isolates were isolated. S. sonnei was themost prevalent Shigella species (60.7%) followed by, S. flexneri (31.5%). Eleven antimicrobial resistance patterns (R1-R11) were identified among S. sonnei isolates. The majority of the strains were resistant to trimethoprim-sulfamethoxazole, tetracycline and streptomycin. All isolates were susceptible to ciprofloxacin, ceftizoxime and chloramphenicol. All strains were typable by ERIC-PCR. Five ERIC-PCR patterns (E1-E5) were found among S. sonnei isolates; however the half of the isolates was clustered in E4 pattern. Conclusion: We found the antibiotic resistance rates are increasing among S. sonnei strains. As reported in recent previous studies, our finding also indicated that a predominant clone or limited clones of S. sonnei are responsible for shigellosis caused by this Shigella species in pediatric patients in Tehran, Iran.

نوع سند :موضوع کنفرانس یا کارگاه (پوستر )
زبان سند : انگلیسی
نویسنده مسئول :رضا رنجبر
کلید واژه ها (انگلیسی):Shigella sonnei ; Antibiotic Resistance ; ERIC-PCR
موضوعات :QW میکروب شناسی و ایمنی شناسی
WS بیماریهای کودکان
بخش های دانشگاهی :معاونت تحقیقات و فناوری > مديريت تحقیقات و فناوری و اطلاع رساني > مدیریت همایش ها و کنگره های دانشگاه
کد شناسایی :4600
ارائه شده توسط : خانم صغری گلمغانی
ارائه شده در تاریخ :10 شهریور 1392 09:21
آخرین تغییر :10 شهریور 1392 09:21

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