اثر مهاری اسانس ترخون در دو گونه مهم آسپرژیلوس

Title

Inhibitory Effect of Artemisia drancunculus Essential Oil on the Two Important Species of Aspergillus

English Abstract

Background & Objectives: Aspergillus spp are ubiquitous saprophytic fungi that cause a variety of diseases, ranging from hypersensivity reactions to flu-like pneumonia and life-theatening invasive aspergillosis. Many studies have shown that essential oil of Artemisia dracunculus or Tarragon have antibacterial and antifungal activity. The aim of this study is to survey the inhibitory effect of Torragon essential oil on Aspergillus fumigatus and Aspedgillus niger. Methods: In this study strains including Aspergillus fumogatus and Aspergillus niger were used from clinical samples. We preapred serial dilution of the essential including 500, 200, 100, 50, 25 and 12.5 in DMSO solvent.The anti aspergillus effect of this essential oil were assessed separately using broth macrodution methods on these strains. Afterwards, the minimum inhibitory concentration (MIC) and minimum fungicidal concetration (MFC) of essential oil were determined. Results: Our results showed that Artemisia dranculus essential oil can inhibit growth of Aspergillus fumigatus and Aspedgillus niger that were isolated clinicaly from patients. MIC of this essential oil from Aspedgillus niger was 500 mg/ml and that of Aspergillus fumigatus was 750 mg/ml. Conclusion: The finding of this study showed that Tarragon essential oil have fungicidal and antifungal function against Aspergillus fumigatus and Aspedgillus niger. Therefor, this essential oil can be used in medical pharmacology,Veterinary, food industries and health affairs as drug and anti fungal element.

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