بررسی انتشار ایزوله های اسینتوباکتر بومانی مقاوم به کرباپنم وابسته به کلون بین المللی تیپ I در شمالغرب ایران

پیمانی, امیر and نهایی, محمدرضا and فرج نیا, صفر and سهرابی, نصرالله and عباسی, لاله (1391) بررسی انتشار ایزوله های اسینتوباکتر بومانی مقاوم به کرباپنم وابسته به کلون بین المللی تیپ I در شمالغرب ایران. در: The 13th Iranian & The Second International Congress of Microbiology, July 14 – 16, 2012, Ardabil - Iran.

Text - Published Version

Official URL: http://congress.arums.ac.ir/index.php/IICM/5/sched...


Dissemination of the Carbapenem Resistant-Acinetobacter baumannii Corresponding to International (IC) Clone I in Northwest of Iran

English Abstract

Background & Objectives: Acinetobacter baumannii is one of the most important nosocomial pathogen that causes a various types of clinical infections. Up to date, three epidemic International clones (IC clones I, II, and III) associated with multidrug-resistant A. baumannii have been identified. For first time, in this survey we studied the characteristics and molecular epidemiology of 68 imipenem-non-susceptible A. baumannii isolated from Imam Reza Hospital in Tabriz, Iran. Methods: A total of 68 non-repetitive imipenem-non-susceptible isolates of A. baumannii were collected on the basis of the results of E-test Methods from different clinical specimens at Imam Reza Hospital, during a 17-month period. All isolates were identified by standard laboratory methods and species identification was confirmed by detection of blaOXA-51-like. The isolates were typed using sequenc egroup-based multiplex PCR assayto compare theclonal relationship of our isolates with International clonal I lineages. PCR assay was performed to detect OXA-type carbapenemases genes. Results: In total, 2 isolates (3%) belonged to IC clone I. Both isolates carried blaOXA-51-like, blaOXA-23-like genes, but not blaOXA-58-like, blaOXA-24-like. ISAba1 was present upstream the blaOXA-23-like gene. Conclusion: This results, for first time, are indicative of clonal spread of OXA-23-producing A. baumannii corresponding to known IC I in northwest of Iran. Early recognition and careful monitoring of such strains to control the further dissemination of this organism in hospitals are needed.

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده مسئول :امیر پیمانی
کلیدواژه ها (انگلیسی):Resistant-Acinetobacter ; Carbapenem ; Dissemination
Subjects:QW Microbiology and Immunology
WB Practice of Medicine
WX Hospital and other health Facilities
Divisions:Vice Chancellor for Research and Technology > Deputy for Research and Technology management and Medical Information > University of Management Conferences and Congresses
ID Code:4638
Deposited By: MS Soghra Golmaghani
Deposited On:21 Jun 1392 09:29
Last Modified:21 Jun 1392 09:29

Repository Staff Only: item control page

Document Downloads

More statistics for this item...