title

تعیین تیپ تنظیم کننده ژنی فرعی (agr) در جدایه های استافیلوکوکوس اورئوس بدست آمده از حفره بینی نشخوار کنندگان سالم در ایران

سلامی پرگو, حامد and دستمالچی ساعی, حبیب and احمدی, ملاحت and رحیمی, حیدر (1391) تعیین تیپ تنظیم کننده ژنی فرعی (agr) در جدایه های استافیلوکوکوس اورئوس بدست آمده از حفره بینی نشخوار کنندگان سالم در ایران. در: The 13th Iranian & The Second International Congress of Microbiology, July 14 – 16, 2012, Ardabil - Iran.

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Title

Accessory Gene Regulator (agr) Typing of Staphylococcus aureus Isolates Recovered From the Nasal Cavity of Healthy Ruminants in Iran

English Abstract

Background & Objectives: Staphylococcus aureus can colonize the nasal mucosa of different animals. The accessory gene regulator (agr) is a quorum sensing cluster of genes which control colonization and virulence in S. aureus. Methods: In the current study, 26 S. aureus nasal isolates from cattle (n = 4), sheep (n = 11), and goats (n = 11) were agr typed by multiplex polymerase chain reaction (PCR). Results: Of 4 S. aureus isolates obtained from cattle, 3 were ascribed to agr type I and 1 to agr type IV. A total of 7 out of 11 sheep nasal isolates were of agr type I, the other 4 being agr type III (n=3) and agr type II (n=1). Goat nasal isolates were distributed mainly across agr types I (n=10). Only one of the goat isolates was agr type II. Conclusion: As results, S. aureus isolates with agr type I were common and might be capable of colonizing the nasal cavity of ruminants, most likely by regulatory adaptation to the nose environment. Further studies will be necessary to define how the type of agr regulatory system might affect nasal colonization in ruminants.

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده مسئول :حامد سلامی پرگو
کلیدواژه ها (انگلیسی):Agr Specificity Group ; Staphylococcus aureus ; Ruminants ; Multiplex PCR
Subjects:QW Microbiology and Immunology
Divisions:Vice Chancellor for Research and Technology > Deputy for Research and Technology management and Medical Information > University of Management Conferences and Congresses
ID Code:4680
Deposited By: MS Soghra Golmaghani
Deposited On:28 Jun 1392 11:46
Last Modified:28 Jun 1392 11:46

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