بررسی اثر ضد میکروبی عصاره و اسانس صمغ( اولئوگم رزین ) گیاه باریجه بر ایزوله های اسینتوباکتر جدا شده از نمونه های بالینی

عنوان انگليسی

Antimicrobial Activity of Oleogum Resin Extract & Essential Oil of Ferula gummosa Boiss Against Clinical Strains of Acinetobacter

خلاصه انگلیسی

Background & Objectives: Acinetobacter spp. is an important cause of nosocomial infections and with widespread resistance to various antibiotics. Ferula gummosa boiss belonging to the family Apiaceae is a wild plant indigenous toIran. This plant has been used in traditional medicine for its medical properties . phytochemical investigations show F. gummosa boiss is source of biologically active compounds. The aim of this study was to evaluation of the antibacterial activity of oleogum resin extract & essential oil of F. gummosa boiss against Clinical strains of Acinetobacter. Methods: Alcoholic, hydroalcoholic and aqueous extracts from oleogum resin of Ferula gummosa were obtained with maceration Methods and Alcoholic, hydroalcoholic and aqueous essential oils was by hydrodistilation methods using a Clevenger apparatus. Solvents evaporated to dryness under reduced pressure in a rotavapor. Antimicrobial activities of extracts and essential oils against of standard and clinical strains of Acinetobacter were evaluated using the agar diffusion methods with disc & well. The minimal inhibitory concentration determined using Broth microdilution methods. Results: Alcoholic essential oil showed higher antibacterial activity while aqueous extract and essential oil don’t have considerably antibacterial activity. Conclusion: Alcoholic and hydroalcoholic extracts and essential oils had growth inhibitory effect on the bacteria. Alcoholic essential oil had significantly greater effect on inhibition of growth of Acinetobacter strains.

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