طراحی سطح پاسخ در تشکیل کمپلکس بین داروی پیروکسیکام و یون های آهن

ادریسی, محمد and رزاقی اصل, نیما (1386) طراحی سطح پاسخ در تشکیل کمپلکس بین داروی پیروکسیکام و یون های آهن. Acta Chimica Slovenica ــ 54 (4). pp. 825-833. شاپا 1318-0207

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Official URL: http://acta.chem-soc.si/54/graph/acta-54(4)-GA.htm


Complexation of iron with piroxicam–evaluation via response surface methodology

English Abstract

A response surface methodology (RSM) based on a Box-Behnken design was applied for study on ferrous ions binding ability to piroxicam in aqueous solution as a function of three numerical factors (extraction time, pH, piroxicam concentration) and extractant type as a categorical variable each in three levels. Analysis of variance (ANOVA) provided a supporting evidence for quadratic model to fit the experimental data with a correlation value squared (r2) of 0.9433. All the experimental data resulted by a selective extraction-spectrophotometric method. The relative standard deviation (RSD) was found to be 0.63%.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :محمد ادریسی
نویسنده مسئول :نیما رزاقی اصل
Additional Information:ImpactFactor: 01.093 Abstracting / indexing : Science Citation Index Expanded , Chemical Abstracts , Current Contents , Chemistry Citation Index , DOAJ
کلیدواژه ها (انگلیسی):Piroxicam, iron, spectrophotometry, box-behnken design
Subjects:QV pharmacology > QV 744 Medicinal Chemistry
QV pharmacology
Divisions:School of Pharmacy > Department of Medicinal Chemistry
ID Code:5380
Deposited By: Dr Nima Razzaghi-Asl
Deposited On:11 Sep 1393 08:38
Last Modified:11 Sep 1393 08:38

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