ادریسی, محمد and رزاقی اصل, نیما and درگاهی, صدیقه (1391) ارزیابی اثر فاکتورها در برهمکنش سیپروفلوکساسین و یون های فریک. International Journal of Research in Chemistry and Environment ــ 2 (1). pp. 242-250. شاپا 2248-9649
|
Text
- Published Version
308kB |
Official URL: http://www.ijrce.org/back_details.php?id=181
Title
Factor Effect Estimation in Ciprofloxacin-Iron Interaction
English Abstract
Interaction of drug molecules with exogenous substances such as metal ions is of significant importance from both physiological and pharmaceutical aspects of view. The effects of different variables on complex formation between ciprofloxacin and Iron (III) ions were evaluated and compared via facile modern statistical techniques such as Response Surface Methodology (RSM), Ruggedness testing, Factorial design and Taguchi method. Results of all methods were in relatively good agreement with each other and revealed that contact time of the reactants and pH may play more important roles in complex formation between ciprofloxacin and ferric ions.
| Item Type: | Article |
|---|---|
| زبان سند : | انگلیسی |
| نویسنده مسئول : | محمد ادریسی |
| نویسنده : | نیما رزاقی اصل |
| نویسنده : | صدیقه درگاهی |
| کلیدواژه ها (انگلیسی): | Ciprofloxacin, Ruggedness, Complexation, Box-Behnken design |
| Subjects: | QV pharmacology > QV 744 Medicinal Chemistry |
| Divisions: | School of Pharmacy > Department of Medicinal Chemistry |
| ID Code: | 5385 |
| Deposited By: | Dr Nima Razzaghi-Asl |
| Deposited On: | 10 Sep 1393 07:12 |
| Last Modified: | 10 Sep 1393 07:23 |
Repository Staff Only: item control page