بررسی کمبود های گاز های خون شریانی در بدو بستری و 24 ساعت بعد در پیشگویی پیامد بیماران

Title

The Initial and 24 h (After the Patient Rehabilitation) Deficit of Arterial Blood Gases as Predictors of Patients Outcome

English Abstract

The present study aimed to determine the relationship between initial and 24 h base deficit after the patient rehabilitation in critically ill inpatients in the surgical ICU to determine the prognosis of patients. 96 patients hospitalized in the surgical ICU during 6 months were enrolled regardless of the reason for admission. The statistical correlation between initial and 24 h base deficit and the patients’ outcome were examined. The raw data were analyzed using descriptive and analytical statistical methods by SPSS. Various statistical tests such as T-test, Chi-Square and Roc curve were used. The results with P-value less than 0.05 were statistically considered valid. The initial and 24 h base deficit of patients with death outcome was significantly higher than those with discharge outcome (P<0.001). The initial arterial pH had no statistically significant correlation with patients’ outcome (p=0.46). In contrast, the 24 h arterial pH was associated with outcome (p= 0.066). There was a poor correlation between arterial blood pressure at admission and patients’ outcome (p=0.06). The values of initial and 24h base deficit with the most predictor ability of patients’ outcome were -11.35 and -4.6. Accordingly, the deficit of initial base up to -11.35 has been associated with mortality rate of 19.7%. Values less than -11.35 has been associated with mortality rate of 65.4% (p=0.001). Furthermore, the 24 h base deficit up to -4.6 has been associated with mortality rate of 15.2%. Values less than -4.6 has been associated with mortality rate of 61.5% (p<0.001). The increased levels of initial and 24 h base deficit have a strong correlation with the outcome of critically ill patients. Therefore, it can be used in determining the prognosis of critically ill patients.

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