پورفرضی, فرهاد and علیمحمدی, حسین and شکوهی گوگانی, بهروز and حاجی جعفری, رضا (1388) ارزیابی تست آنتی ژن هلیکوباکتر مدفوع در تشخیص عفونت هلیکو باکتر پیلوری. در: The 3rd EURASIA congress of infectious diseases, 1-4 october 2009, آذربایجان - باکو.
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Title
Evaluation of Helicobacter Pylori Stool Antigen Test in the Diagnosis of Helicobacter Pylori Infection
English Abstract
INTRODUCTION: There are several tests for detection of H. pylori infection which can be classified as invasive and non-invasive methods. The invasive tests are normally expensive which need endoscopic procedure. Therefore, there is a need for a quick, inexpensive and reliable noninvasive test to detect H. pylori. This study aimed to evaluate the enzyme immunoassay for the detection of H. pylori antigen in stool in the Ardabil population. Results of tests were compared with gold standard: histology and RUT. AIMS & METHODS: This study aimed to evaluate the enzyme immunoassay for the detection of H. pylori antigen in stool in the Ardabil population. Results of tests were compared with gold standard: histology and RUT. 60 patients who had been referred to Aras clinic by gastroenterologists due to dyspepsia were recruited. The subjects underwent endoscopic examination and two biopsies were taken from antrum. The first specimen was used for RUT and the second was used for histology. Meanwhile, a questionnaire was administered and a stool sample were taken and sent for HpSA (Helicobacter pylori Stool Antigen test). RESULTS: Thirty patients were positive for H. pylori and equal numbers were negative using gold standard. HpSA was positive in 29 of 30 and negative in 28 of 30. The sensitivity and specificity of the HpSA were 96.6% and 93.3% respectively. The positive and negative predictive values were 93.5% and 96.5% respectively. CONCLUSION: HpSA is an easy, effective method for the diagnosis and response to treatment of H. pylori infection in the studied population.
| Item Type: | Conference or Workshop Item (Poster) |
|---|---|
| زبان سند : | انگلیسی |
| نویسنده مسئول : | فرهاد پورفرضی |
| کلیدواژه ها (انگلیسی): | Helicobacter pylori , Validation , stool antigen test |
| Subjects: | WI Digestive System QW Microbiology and Immunology |
| Divisions: | Faculty of Medicine > Department of Pediatrics , Community Medicine Faculty of Medicine > Department of Basic Sciences > Department of Pathology Faculty of Medicine > Department of Basic Sciences > Department of Microbiology |
| ID Code: | 542 |
| Deposited By: | Dr Farhad Pourfarzi |
| Deposited On: | 09 Oct 1388 05:00 |
| Last Modified: | 31 Mar 1393 07:58 |
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