کراتیت بینابینی، سرگیجه و واسکولیت: سندرم کوگان تیپیک

اعظمی, احد and ملکی, نصراله and کلانتر هرمزی, محمدرضا and طاووسی, زهرا (1392) کراتیت بینابینی، سرگیجه و واسکولیت: سندرم کوگان تیپیک. Case Reports in Medicine ــ 2014 (2014). pp. 1-4. شاپا 1687-9627

Text - Published Version

Official URL: http://www.hindawi.com/journals/crim/2014/830831


Interstitial Keratitis, Vertigo, and Vasculitis: Typical Cogan’s Syndrome

English Abstract

Cogan’s syndrome (CS) is a chronic inflammatory disorder of unknown etiology that most commonly affects young adults. Clinical hallmarks are bilateral interstitial keratitis and vestibuloauditory dysfunction. Association between CS and systemic vasculitis as well as aortitis also exists. The diagnosis of CS is based upon presence of characteristic inflammatory eye disease and vestibuloauditory dysfunction. We describe classic Cogan’s syndrome in a 47-year-old female from Ardabil. The patient was admitted with headache, vertigo, nausea, vomiting, right leg claudication, musculoskeletal pains, bilateral hearing loss, and blindness for the past two months. Ophthalmologic examination revealed that visual acuity was 0.1 bilaterally. Conjunctival hyperemia, bilateral cataract, and interstitial keratitis were detected with a slit lamp examination. Pure tone audiogram (PTA) and auditory brain stem response (ABR) showed bilateral sensorineural hearing loss. The other differential diagnosis of CS was studied and ruled out. Pulse i.v. methylprednisolone and cyclophosphamide were given and were followed by oral prednisolone and cyclophosphamide. Clinical follow-up showed partial improvement.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :احد اعظمی
نویسنده مسئول :نصراله ملکی
نویسنده :محمدرضا کلانتر هرمزی
نویسنده :زهرا طاووسی
Additional Information:Abstracting and Indexing: PubMed , PubMed Central , Academic OneFile , Academic Search Alumni Edition , Academic Search Complete , Calcium and Calcified Tissue Abstracts , Cases Database , CINAHL Plus with Full Text CNKI Scholar , Current Abstracts , Directory of Open Access Journals (DOAJ) , EBSCOhost Connection , EMBASE , Expanded , Academic Index , Google Scholar , Health and Wellness Resource Center , HINARI Access to Research in Health Programme , Industrial and Applied Microbiology Abstracts , InfoTrac Custom journals , J-Gate Portal Nursing Resource Center
کلیدواژه ها (انگلیسی):cogan’s syndrome , interstitial keratitis , hearing loss , vasculitis
Subjects:WE Musculoskeletal system
WV Otolaryngology
WW Ophthalmology
Divisions:Faculty of Medicine > Department of Internal Medicine , Cardiology , Infectious
ID Code:5449
Deposited By: Dr Nasrollah Maleki
Deposited On:17 Dec 1392 10:18
Last Modified:10 Nov 1397 10:23

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